比较女性精神分裂症患者同胞和后代的思维理论和神经认知。

IF 1.4 4区 心理学 Q4 CLINICAL NEUROLOGY
Applied Neuropsychology-Adult Pub Date : 2025-03-01 Epub Date: 2023-01-18 DOI:10.1080/23279095.2023.2168544
Özlem Altuntaş, Ejder Akgun Yıldırım, Görkem Yılmaz, Ender Cesur
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引用次数: 0

摘要

本研究旨在比较精神分裂症女性患者的兄弟姐妹和后代的心智理论(ToM)功能,以评估神经认知功能与 ToM 之间的关联。本研究采用一系列心智测试("眼读心 "测试、"暗示测试 "和 "假动作测试")和神经认知测试("数字跨度测试"、"Corsi区块测试"、"数字符号替换测试"、"Rey听觉言语学习测试"、"轨迹制作测试"、"Stroop测试 "和 "威斯康星卡片分类测试"),对女性精神分裂症患者的29名兄弟姐妹和28名健康对照组(HC)的31名后代进行了评估。比较本研究中子女组、兄弟姐妹组和健康对照组的 ToM 功能,发现子女组和兄弟姐妹组在暗示、假动作和眼睛测试中没有显著差异,而兄弟姐妹组的暗示测试成绩明显低于健康对照组。后代和兄弟姐妹的神经认知功能受到的影响均大于 HC。虽然确定患者亲属的 ToM 缺陷不如其神经认知功能突出,但 ToM 是精神分裂症的一种内表型候选者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison of theory of mind and neurocognition in siblings and offspring of female schizophrenia patients.

This study aims to compare the Theory of Mind (ToM) functions in the siblings and offspring of female Schizophrenia patients in an evaluation of the association between neurocognitive functions and ToM. A battery of ToM tests (Reading the Mind in the Eyes Test, Hinting Test and Faux Pas Test) and neurocognitive tests (Digit Span Test, Corsi Block Test, Digit Symbol Substitution Test, Rey's Auditory Verbal Learning Test, Trail Making Test, The Stroop Test, Wisconsin Card Sorting Test) were used to assess 31 offspring, 29 siblings of female schizophrenia patients and 28 healthy controls (HC). When the ToM functions of the offspring, siblings and HC groups in the present study are compared, no significant difference is identified between the offspring and sibling groups in Hinting, Faux Pas and Eyes tests, while Hinting test performance of the sibling group was significantly lower than those of the HCs. Neurocognitive functions are more affected both in offspring and siblings than HC. Although it was determined that ToM deficits of the patients' relatives were not as prominent as their neurocognitive functions, ToM is an endophenotype candidate in schizophrenia.

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来源期刊
Applied Neuropsychology-Adult
Applied Neuropsychology-Adult CLINICAL NEUROLOGY-PSYCHOLOGY
CiteScore
4.50
自引率
11.80%
发文量
134
期刊介绍: pplied Neuropsychology-Adult publishes clinical neuropsychological articles concerning assessment, brain functioning and neuroimaging, neuropsychological treatment, and rehabilitation in adults. Full-length articles and brief communications are included. Case studies of adult patients carefully assessing the nature, course, or treatment of clinical neuropsychological dysfunctions in the context of scientific literature, are suitable. Review manuscripts addressing critical issues are encouraged. Preference is given to papers of clinical relevance to others in the field. All submitted manuscripts are subject to initial appraisal by the Editor-in-Chief, and, if found suitable for further considerations are peer reviewed by independent, anonymous expert referees. All peer review is single-blind and submission is online via ScholarOne Manuscripts.
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