角膜电解治疗LASIK术后颗粒状角膜营养不良2型(Avellino角膜营养不良)恶化。

IF 3 3区医学 Q1 OPHTHALMOLOGY

Journal of refractive surgery Pub Date : 2023-01-01 DOI:10.3928/1081597X-20221129-01

Osamu Hieda, Akira Kobayashi, Chie Sotozono, Shigeru Kinoshita

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引用次数: 0

摘要

目的:报告2例2型颗粒性角膜营养不良(GCD2;采用角膜电解法成功地消除了激光原位角膜磨除术(LASIK)后的Avellino角膜营养不良。方法:本研究涉及一名66岁男性和一名43岁男性GCD2患者，他们在就诊前10年或更长时间接受了双侧LASIK治疗近视。两例患者术后在LASIK皮瓣界面处逐渐出现GCD2角膜混浊，导致视力下降。为了治疗，两名患者的LASIK皮瓣都通过手术解除，直接去除混浊。然后将角膜电解应用于每个LASIK皮瓣和基质床的后部。结果:术后与GCD加重相关的眼部症状和角膜混浊消失，矫正和未矫正的距离视力均有改善，屈光不正基本无变化。结论:本研究结果表明，角膜电解用于LASIK术后GCD2加重的治疗是安全有效的，并且成功地去除了GCD2相关的LASIK皮瓣界面浊度，术后屈光不正几乎没有变化。[J].中国光学精密工程，2003,19(1):1- 4。

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Corneal Electrolysis for Granular Corneal Dystrophy Type 2 (Avellino Corneal Dystrophy) Exacerbation After LASIK.

Purpose: To report two cases in which exacerbation of granular corneal dystrophy type 2 (GCD2; Avellino corneal dystrophy) after laser in situ keratomileusis (LASIK) was successfully removed by corneal electrolysis.

Methods: This study involved a 66-year-old man and a 43-year-old man with GCD2 who had undergone bilateral LASIK for myopia 10 or more years prior to presentation. In both patients, GCD2 corneal opacity gradually developed postoperatively at the LASIK flap interface, thus resulting in a decrease of visual acuity. For treatment, the LASIK flaps in both patients were surgically lifted to directly remove the opacity. Corneal electrolysis was then applied to the back of each LASIK flap and stromal bed.

Results: Postoperatively, the ocular symptoms and corneal opacities related to GCD exacerbation disappeared, with improvement of corrected and uncorrected distance visual acuity and almost no change of refractive error.

Conclusions: The findings reveal that corneal electrolysis is safe and effective for treating exacerbations of GCD2 following LASIK when applied to a surgically lifted flap, and that it successfully removes GCD2-related LASIK flap interface opacities with almost no change of refractive error postoperatively. [J Refract Surg. 2023;39(1):61-65.].

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来源期刊

$Journal of refractive surgery$

Journal of refractive surgery 医学-外科

CiteScore

5.10

自引率

12.50%

发文量

160

审稿时长

4-8 weeks

期刊介绍： The Journal of Refractive Surgery, the official journal of the International Society of Refractive Surgery, a partner of the American Academy of Ophthalmology, has been a monthly peer-reviewed forum for original research, review, and evaluation of refractive and lens-based surgical procedures for more than 30 years. Practical, clinically valuable articles provide readers with the most up-to-date information regarding advances in the field of refractive surgery. Begin to explore the Journal and all of its great benefits such as: • Columns including “Translational Science,” “Surgical Techniques,” and “Biomechanics” • Supplemental videos and materials available for many articles • Access to current articles, as well as several years of archived content • Articles posted online just 2 months after acceptance.