{"title":"COVID-19和阴茎勃起:一个未被探索的关联。","authors":"Wai Gin Lee","doi":"10.1097/CU9.0000000000000139","DOIUrl":null,"url":null,"abstract":"Our understanding of coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to evolve. Much has been written about the respiratory and proinflammatory sequelae of this condition. SARS-CoV-2 infection is mediated by the binding of the viral spike protein to angiotensin-convertingenzyme2(ACE2). [1] ACE2ishighlyexpressed in the endothelium (as well as in the lungs, kidney, liver, and heart), and this is thought to be the underlying cause of the thrombotic com-plications of COVID-19. Endothelial dysfunction resulting from endothelial activation and reduced endothelium-dependent vasodila-tation underlies the hallmark of COVID-19 as a proinflammatory and procoagulant milieu. [2]","PeriodicalId":39147,"journal":{"name":"Current Urology","volume":"16 4","pages":"265-266"},"PeriodicalIF":0.9000,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9d/65/curr-urol-16-265.PMC9815694.pdf","citationCount":"1","resultStr":"{\"title\":\"COVID-19 and priapism: An unexplored association.\",\"authors\":\"Wai Gin Lee\",\"doi\":\"10.1097/CU9.0000000000000139\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Our understanding of coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to evolve. Much has been written about the respiratory and proinflammatory sequelae of this condition. SARS-CoV-2 infection is mediated by the binding of the viral spike protein to angiotensin-convertingenzyme2(ACE2). [1] ACE2ishighlyexpressed in the endothelium (as well as in the lungs, kidney, liver, and heart), and this is thought to be the underlying cause of the thrombotic com-plications of COVID-19. Endothelial dysfunction resulting from endothelial activation and reduced endothelium-dependent vasodila-tation underlies the hallmark of COVID-19 as a proinflammatory and procoagulant milieu. [2]\",\"PeriodicalId\":39147,\"journal\":{\"name\":\"Current Urology\",\"volume\":\"16 4\",\"pages\":\"265-266\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2022-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9d/65/curr-urol-16-265.PMC9815694.pdf\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Urology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1097/CU9.0000000000000139\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Urology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/CU9.0000000000000139","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
Our understanding of coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to evolve. Much has been written about the respiratory and proinflammatory sequelae of this condition. SARS-CoV-2 infection is mediated by the binding of the viral spike protein to angiotensin-convertingenzyme2(ACE2). [1] ACE2ishighlyexpressed in the endothelium (as well as in the lungs, kidney, liver, and heart), and this is thought to be the underlying cause of the thrombotic com-plications of COVID-19. Endothelial dysfunction resulting from endothelial activation and reduced endothelium-dependent vasodila-tation underlies the hallmark of COVID-19 as a proinflammatory and procoagulant milieu. [2]
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