Chieh-Szu Chang, Chia-Chih Liao, Huang-Ping Yu, Hung-Chen Lee, Fu-Chao Liu
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Investigation of Cerebrospinal Fluid Electrolytes and Acid-Base Expressions in Asian Adults.
Background: In previous literature, reference values for cerebrospinal fluid (CSF) may be based on patients who were not truly healthy, other species, or outdated information. In the present study, we performed a lumbar puncture in patients requiring spinal anesthesia by a reasonable indication to evaluate CSF parameters in healthy adults.
Methods: All patients between the ages of 20 and 70 years scheduled for elective orthopedic or urologic surgery requiring spinal anesthesia were enrolled in this study. We measured electrolytes and gas tension analysis in CSF and whole blood samples in adult humans.
Results: A total of 28 patients were included with an average age of 44.2 years. The concentration of Na^+ in blood was slightly lower when compared with that in CSF. There were significantly higher levels of K^+ and Ca^(2+) in the blood when we compared with CSF. Significantly lower levels of Cl^- and Mg^(2+) in the blood were observed when compared with CSF. The glucose level of CSF was about half of that in blood.
Conclusions: We provided updated reference values for various solutes in blood and CSF in adults. Analysis of CSF parameters and relevant paired blood samples is highly informative, helping clinicians diagnose a variety of central nervous system diseases.
期刊介绍：
Asian Journal of Anesthesiology (AJA), launched in 1962, is the official and peer-reviewed publication of the Taiwan Society of Anaesthesiologists. It is published quarterly (March/June/September/December) by Airiti and indexed in EMBASE, Medline, Scopus, ScienceDirect, SIIC Data Bases. AJA accepts submissions from around the world. AJA is the premier open access journal in the field of anaesthesia and its related disciplines of critical care and pain in Asia. The number of Chinese anaesthesiologists has reached more than 60,000 and is still growing. The journal aims to disseminate anaesthesiology research and services for the Chinese community and is now the main anaesthesiology journal for Chinese societies located in Taiwan, Mainland China, Hong Kong and Singapore. AJAcaters to clinicians of all relevant specialties and biomedical scientists working in the areas of anesthesia, critical care medicine and pain management, as well as other related fields (pharmacology, pathology molecular biology, etc). AJA''s editorial team is composed of local and regional experts in the field as well as many leading international experts. Article types accepted include review articles, research papers, short communication, correspondence and images.
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