原肠胚形成和裂索畸形。

Zubair Tahir, Claudia Craven
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引用次数: 0

摘要

劈裂脊髓畸形(SCM)是一种罕见的闭合性脊髓发育异常,其中存在两条半脊髓,而不是一条脊髓。SCM分为类型1和类型2。1型SCM的定义是在半索之间存在骨性或骨软骨性骨刺,而2型SCM没有骨刺,两条半索包含在一个硬脑膜内。在本章中,我们提出了假定的SCM产生的机制,包括原肠形成缺陷和Pang的统一理论。本文描述了典型和罕见的临床表现和变异。最后,我们概述了SCM 1和SCM 2的一步一步的手术方法以及两种情况的总体预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Gastrulation and Split Cord Malformation.

Split cord malformation (SCM) is a rare form of closed spinal dysraphism, in which two hemi-cords are present, instead of a single spinal cord. SCM is categorised into type 1 and type 2. Type 1 SCM is defined by the presence of a bony or osseocartilaginous spur between the hemi-cords, whereas type 2 SCM has no bony spur, and the two hemi-cords are contained within a single dura. In this chapter, we present the putative mechanisms by which SCM arises, including gastrulation defects and Pang's unified theory. The typical and rare clinical presentations and variations are described. Finally, we outline the step-by-step surgical approach to both SCM 1 and 2 and the overall prognosis of both conditions.

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