[追踪携带抗药性的细菌在动物、人类和环境之间的转移]。

Pub Date : 2024-03-29 DOI:10.5802/crbiol.114
Sylvain Meyer, Lucie Laval, Mélanie Pimenta, Yolanda González-Flores, Margaux Gaschet, Elodie Couvé-Deacon, Olivier Barraud, Christophe Dagot, Marie-Cécile Ploy
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引用次数: 0

摘要

抗击抗生素耐药性的斗争必须融入 "一体健康 "理念,才能取得成效。这意味着要采用一种整体方法,将人类、动物和环境等不同的生态系统纳入其中。这三个领域之间可能存在抗药性基因的转移,而与暴露体相关的不同压力可能会影响这些转移。各种有针对性的或泛基因组分子生物学技术可用于更好地描述细菌克隆的传播特征,并确定生态系统之间的基因和流动遗传因子交换。
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[Tracking transfers of resistance-carrying bacteria between animals, humans and the environment].

The fight against antibiotic resistance must incorporate the "One Health" concept to be effective. This means having a holistic approach embracing the different ecosystems, human, animal, and environment. Transfers of resistance genes may exist between these three domains and different stresses related to the exposome may influence these transfers. Various targeted or pan-genomic molecular biology techniques can be used to better characterise the dissemination of bacterial clones and to identify exchanges of genes and mobile genetic elements between ecosystems.

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