帕金森病的语言推理障碍。

IF 2.7 4区医学 Q2 CLINICAL NEUROLOGY

Behavioural Neurology Pub Date : 2022-01-01 DOI:10.1155/2022/3422578

Antonina Luca, Giulia Donzuso, Concetta D'Agate, Claudio Terravecchia, Calogero Cicero Edoardo, Giovanni Mostile, Giorgia Sciacca, Alessandra Nicoletti, Mario Zappia

{"title":"帕金森病的语言推理障碍。","authors":"Antonina Luca, Giulia Donzuso, Concetta D'Agate, Claudio Terravecchia, Calogero Cicero Edoardo, Giovanni Mostile, Giorgia Sciacca, Alessandra Nicoletti, Mario Zappia","doi":"10.1155/2022/3422578","DOIUrl":null,"url":null,"abstract":"Background: The aim of this study was to assess verbal reasoning (VR) functioning in patients with Parkinson's disease (PD) and healthy controls (HCs).Methods: The non-demented PD patients and HCs matched by age and global cognition were enrolled in this study. VR was assessed with the verbal reasoning test (VRT), total score, and subsets.Results: Eighty-seven PD patients (51 men; mean age 63.8 ± 7.9 years) and 87 HCs (46 men; mean age 63.7 ± 8.0 years) were enrolled. At univariate analysis, PD patients presented a significantly lower score in the VRT subset classification (12.3 ± 2.1) than HCs (12.9 ± 1.7) with an odds ratio (OR) of 0.8 (95% confidence interval [CI] 0.70-0.98; p = 0.003). The strength of association was also confirmed at multivariate analysis (OR = 0.8, 95% CI 0.70-0.98; p = 0.003). Moreover, in PD patients, a statistically significant positive correlation was found between VRT-classification and MoCA scores (r = 0.330; p = 0.002).Conclusions: PD patients presented lower VR performance than HCs.","PeriodicalId":50733,"journal":{"name":"Behavioural Neurology","volume":"2022 ","pages":"3422578"},"PeriodicalIF":2.7000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759383/pdf/","citationCount":"0","resultStr":"{\"title\":\"Verbal Reasoning Impairment in Parkinson's Disease.\",\"authors\":\"Antonina Luca, Giulia Donzuso, Concetta D'Agate, Claudio Terravecchia, Calogero Cicero Edoardo, Giovanni Mostile, Giorgia Sciacca, Alessandra Nicoletti, Mario Zappia\",\"doi\":\"10.1155/2022/3422578\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: The aim of this study was to assess verbal reasoning (VR) functioning in patients with Parkinson's disease (PD) and healthy controls (HCs).Methods: The non-demented PD patients and HCs matched by age and global cognition were enrolled in this study. VR was assessed with the verbal reasoning test (VRT), total score, and subsets.Results: Eighty-seven PD patients (51 men; mean age 63.8 ± 7.9 years) and 87 HCs (46 men; mean age 63.7 ± 8.0 years) were enrolled. At univariate analysis, PD patients presented a significantly lower score in the VRT subset classification (12.3 ± 2.1) than HCs (12.9 ± 1.7) with an odds ratio (OR) of 0.8 (95% confidence interval [CI] 0.70-0.98; p = 0.003). The strength of association was also confirmed at multivariate analysis (OR = 0.8, 95% CI 0.70-0.98; p = 0.003). Moreover, in PD patients, a statistically significant positive correlation was found between VRT-classification and MoCA scores (r = 0.330; p = 0.002).Conclusions: PD patients presented lower VR performance than HCs.\",\"PeriodicalId\":50733,\"journal\":{\"name\":\"Behavioural Neurology\",\"volume\":\"2022 \",\"pages\":\"3422578\"},\"PeriodicalIF\":2.7000,\"publicationDate\":\"2022-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9759383/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Behavioural Neurology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1155/2022/3422578\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Behavioural Neurology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1155/2022/3422578","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}

引用次数: 0

摘要

背景:本研究的目的是评估帕金森病(PD)患者和健康对照(hc)的言语推理(VR)功能。方法:选取年龄和整体认知相匹配的非痴呆性PD患者和hc。VR通过言语推理测试(VRT)、总分和子集进行评估。结果:87例PD患者(男性51例;平均年龄63.8±7.9岁)和87例HCs(男性46例;平均年龄63.7±8.0岁)。在单因素分析中，PD患者在VRT亚群分类中的得分(12.3±2.1)明显低于hc患者(12.9±1.7)，优势比(OR)为0.8(95%可信区间[CI] 0.70-0.98;P = 0.003)。多变量分析也证实了相关性(OR = 0.8, 95% CI 0.70-0.98;P = 0.003)。此外，在PD患者中，vrt分类与MoCA评分之间存在统计学上显著的正相关(r = 0.330;P = 0.002)。结论:PD患者的VR表现低于hc患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Verbal Reasoning Impairment in Parkinson's Disease.

查看原文本刊更多论文

Verbal Reasoning Impairment in Parkinson's Disease.

Background: The aim of this study was to assess verbal reasoning (VR) functioning in patients with Parkinson's disease (PD) and healthy controls (HCs).

Methods: The non-demented PD patients and HCs matched by age and global cognition were enrolled in this study. VR was assessed with the verbal reasoning test (VRT), total score, and subsets.

Results: Eighty-seven PD patients (51 men; mean age 63.8 ± 7.9 years) and 87 HCs (46 men; mean age 63.7 ± 8.0 years) were enrolled. At univariate analysis, PD patients presented a significantly lower score in the VRT subset classification (12.3 ± 2.1) than HCs (12.9 ± 1.7) with an odds ratio (OR) of 0.8 (95% confidence interval [CI] 0.70-0.98; p = 0.003). The strength of association was also confirmed at multivariate analysis (OR = 0.8, 95% CI 0.70-0.98; p = 0.003). Moreover, in PD patients, a statistically significant positive correlation was found between VRT-classification and MoCA scores (r = 0.330; p = 0.002).

Conclusions: PD patients presented lower VR performance than HCs.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Behavioural Neurology 医学-临床神经学

CiteScore

5.40

自引率

3.60%

发文量

审稿时长

>12 weeks

期刊介绍： Behavioural Neurology is a peer-reviewed, Open Access journal which publishes original research articles, review articles and clinical studies based on various diseases and syndromes in behavioural neurology. The aim of the journal is to provide a platform for researchers and clinicians working in various fields of neurology including cognitive neuroscience, neuropsychology and neuropsychiatry. Topics of interest include: ADHD Aphasia Autism Alzheimer’s Disease Behavioural Disorders Dementia Epilepsy Multiple Sclerosis Parkinson’s Disease Psychosis Stroke Traumatic brain injury.