腺苷和星形胶质细胞控制神经可塑性的关键时期。

IF 3.9 3区医学 Q1 CLINICAL NEUROLOGY

Neuroscientist Pub Date : 2023-10-01 Epub Date: 2022-10-15 DOI:10.1177/10738584221126632

Irene Martínez-Gallego, Antonio Rodríguez-Moreno

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引用次数: 1

摘要

可塑性窗口是正确形成确定的大脑回路的基础；这些时期推动了成人在发育过程中的感觉和运动学习，并最终推动了成人的学习和记忆。然而，建立可塑性窗口也限制了中枢神经系统从损伤中恢复的能力。最近的证据强调了星形胶质细胞和腺苷似乎在控制这些关键可塑期的持续时间方面发挥的重要作用。

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Adenosine and Astrocytes Control Critical Periods of Neural Plasticity.

Windows of plasticity are fundamental for the correct formation of definitive brain circuits; these periods drive sensory and motor learning during development and ultimately learning and memory in adults. However, establishing windows of plasticity also imposes limitations on the central nervous system in terms of its capacity to recover from injury. Recent evidence highlights the important role that astrocytes and adenosine seem to play in controlling the duration of these critical periods of plasticity.

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来源期刊

Neuroscientist 医学-临床神经学

CiteScore

11.50

自引率

0.00%

发文量

期刊介绍： Edited by Stephen G. Waxman, The Neuroscientist (NRO) reviews and evaluates the noteworthy advances and key trends in molecular, cellular, developmental, behavioral systems, and cognitive neuroscience in a unique disease-relevant format. Aimed at basic neuroscientists, neurologists, neurosurgeons, and psychiatrists in research, academic, and clinical settings, The Neuroscientist reviews and updates the most important new and emerging basic and clinical neuroscience research.