评价血凝块、富血小板血浆和富血小板纤维蛋白介导的再生根管治疗在根尖周围病变的牙齿:一项CBCT研究。

Swati Markandey, Haridas Das Adhikari
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引用次数: 0

摘要

目的:本研究通过口内根尖周x线摄影(IOPAR)和锥形束计算机断层扫描(CBCT)比较使用血凝块(bc)、富血小板血浆(PRP)和富血小板纤维蛋白(PRF)进行再生牙髓治疗(REPs)的临床和放射学结果。材料和方法:45颗根尖周围病变的单根坏死牙齿随机分配接受BC、PRP或PRF作为单独的支架。通过定性IOPAR评分和定量CBCT测量对23例患者的35颗牙进行随访,随访期12-24个月。评估根尖周病变和未成熟牙的愈合情况、根尖孔直径(AFD)、根壁厚度(RWT)和根长(RL)的变化。p值小于0.05认为有统计学意义。结果:PRP组除1颗牙外,其余牙均无症状。除BC组2颗牙和PRP组3颗牙外,其余牙尖周病变均愈合。IOPAR和CBCT均显示三组患者骨愈合及AFD、RWT、RL的变化无显著差异。BC组有2颗牙的牙髓敏感性对冷试验有阳性反应,但对电牙髓试验无阳性反应。与PRP和PRF组相比,BC组的牙管内钙化(ICC)明显增多,未成熟牙的ICC也明显增多。结论:我们的研究结果显示,BC、PRP和PRF作为支架在REPs中具有相似的潜力,ICC可能是长期结果的关注点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Evaluation of blood clot, platelet-rich plasma, and platelet-rich fibrin-mediated regenerative endodontic procedures in teeth with periapical pathology: a CBCT study.

Evaluation of blood clot, platelet-rich plasma, and platelet-rich fibrin-mediated regenerative endodontic procedures in teeth with periapical pathology: a CBCT study.

Evaluation of blood clot, platelet-rich plasma, and platelet-rich fibrin-mediated regenerative endodontic procedures in teeth with periapical pathology: a CBCT study.

Evaluation of blood clot, platelet-rich plasma, and platelet-rich fibrin-mediated regenerative endodontic procedures in teeth with periapical pathology: a CBCT study.

Objectives: This study compared the clinical and radiological outcomes of regenerative endodontic procedures (REPs) using blood clots (BCs), platelet-rich plasma (PRP), and platelet-rich fibrin (PRF) through intraoral periapical radiography (IOPAR) and cone-beam computed tomography (CBCT).

Materials and methods: Forty-five single-rooted necrotic teeth with periapical pathology were randomly allocated to receive BC, PRP, or PRF as an individual scaffold. Outcomes were evaluated in 35 teeth in 23 patients with a follow-up period of 12-24 months through qualitative IOPAR scoring and quantitative CBCT measurements. Healing of periapical lesions and in immature teeth, changes in the apical foramen diameter (AFD), root wall thickness (RWT), and root length (RL) were assessed. A p value less than 0.05 was considered to indicate statistical significance.

Results: All teeth were asymptomatic except 1 in the PRP group. Periapical lesion healing was seen in all except 2 teeth in the BC group and 3 in the PRP group. Both IOPAR and CBCT revealed no significant differences in bone healing or changes in AFD, RWT, and RL among the 3 groups. A positive pulp sensibility response to the cold test was seen in 2 teeth in the BC group, but none to the electric pulp test. Intracanal calcification (ICC) was evident in more teeth in the BC group than in the PRP and PRF groups, and was also significantly higher in immature teeth.

Conclusions: Our results revealed that BC, PRP, and PRF have similar potential as scaffolds in REPs, and ICC may be a concern for long-term outcomes.

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