Constantinos Contrafouris, Constantine N Antonopoulos, Spyridon Rammos, Meletios Kanakis, Konstantinos Petsios, John D Kakisis, George Geroulakos
{"title":"评价主动脉缩窄支架置入的有效性。","authors":"Constantinos Contrafouris, Constantine N Antonopoulos, Spyridon Rammos, Meletios Kanakis, Konstantinos Petsios, John D Kakisis, George Geroulakos","doi":"10.1055/s-0042-1750097","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong> Coarctation of the aorta (CoA) is a congenital cardiovascular malformation involving narrowing of the thoracic aorta just distal to the left subclavian artery. The aim of our study was to evaluate the hemodynamic effects of endovascular treatment for CoA by using invasive aortic catheterization.</p><p><strong>Methods: </strong> All patients with CoA who underwent treatment by aortic stent implantation between September 1, 2003, and February 1, 2019, at the \"Onassis Cardiac Surgery Center,\" in Athens, Greece, were evaluated. Patients were treated with either bare (uncovered) Cheatham-Platinum (bCP) or covered Cheatham-Platinum (cCP) stent implantations. Invasive aortic pressure measurements were recorded before and after the endovascular intervention.</p><p><strong>Results: </strong> A total of 48, eight zig CP stents, comprising 24 bCP and 24 cCP stents were implanted in 47 patients. The mean aortic diameter (mm) at the CoA lesion increased from 9.7 ± 3.3 to 19.2 ± 2.9 mm (<i>p</i> <0.01) after the endovascular procedure. The invasive mean blood pressure (BP; mm Hg) from catheterization in the descending aorta increased (before = 114.2 ± 12.8 vs. after = 135.5 ± 28.1; <i>p</i> <0.01), while the invasive mean BP (mm Hg) from catheterization in the ascending aorta was decreased (before = 156.8 ± 25.0 vs. after = 138.4 ± 27.5; <i>p</i> <0.01) after the intervention. The mean aortic BP gradient decreased in both types of stents after intervention (BP gradient among patients with cCP stents = 30.9 +/- 23.6 mmHg and BP gradient among patients with bCP stents = 38.0 +/-23.1 mmHg). However, there was no statistically significant difference between the two types of stents; <i>p</i> = 0.36.</p><p><strong>Conclusions: </strong> Invasive aortic catheterization provided evidence that endovascular stenting with either bare or covered stents is efficient in treating patients with CoA.</p>","PeriodicalId":52392,"journal":{"name":"AORTA","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9767786/pdf/","citationCount":"0","resultStr":"{\"title\":\"Evaluating the Effectiveness of Stenting for Aortic Coarctation.\",\"authors\":\"Constantinos Contrafouris, Constantine N Antonopoulos, Spyridon Rammos, Meletios Kanakis, Konstantinos Petsios, John D Kakisis, George Geroulakos\",\"doi\":\"10.1055/s-0042-1750097\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong> Coarctation of the aorta (CoA) is a congenital cardiovascular malformation involving narrowing of the thoracic aorta just distal to the left subclavian artery. The aim of our study was to evaluate the hemodynamic effects of endovascular treatment for CoA by using invasive aortic catheterization.</p><p><strong>Methods: </strong> All patients with CoA who underwent treatment by aortic stent implantation between September 1, 2003, and February 1, 2019, at the \\\"Onassis Cardiac Surgery Center,\\\" in Athens, Greece, were evaluated. Patients were treated with either bare (uncovered) Cheatham-Platinum (bCP) or covered Cheatham-Platinum (cCP) stent implantations. Invasive aortic pressure measurements were recorded before and after the endovascular intervention.</p><p><strong>Results: </strong> A total of 48, eight zig CP stents, comprising 24 bCP and 24 cCP stents were implanted in 47 patients. The mean aortic diameter (mm) at the CoA lesion increased from 9.7 ± 3.3 to 19.2 ± 2.9 mm (<i>p</i> <0.01) after the endovascular procedure. The invasive mean blood pressure (BP; mm Hg) from catheterization in the descending aorta increased (before = 114.2 ± 12.8 vs. after = 135.5 ± 28.1; <i>p</i> <0.01), while the invasive mean BP (mm Hg) from catheterization in the ascending aorta was decreased (before = 156.8 ± 25.0 vs. after = 138.4 ± 27.5; <i>p</i> <0.01) after the intervention. The mean aortic BP gradient decreased in both types of stents after intervention (BP gradient among patients with cCP stents = 30.9 +/- 23.6 mmHg and BP gradient among patients with bCP stents = 38.0 +/-23.1 mmHg). However, there was no statistically significant difference between the two types of stents; <i>p</i> = 0.36.</p><p><strong>Conclusions: </strong> Invasive aortic catheterization provided evidence that endovascular stenting with either bare or covered stents is efficient in treating patients with CoA.</p>\",\"PeriodicalId\":52392,\"journal\":{\"name\":\"AORTA\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9767786/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"AORTA\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1055/s-0042-1750097\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"AORTA","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/s-0042-1750097","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
摘要
背景:主动脉缩窄(CoA)是一种先天性心血管畸形,涉及左锁骨下动脉远端的胸主动脉变窄。我们研究的目的是评估血管内治疗CoA的血流动力学效果,采用有创主动脉导管置入。方法:对2003年9月1日至2019年2月1日期间在希腊雅典“奥纳西斯心脏外科中心”接受主动脉支架植入治疗的所有CoA患者进行评估。患者接受裸(未覆盖)Cheatham-Platinum (bCP)或覆盖Cheatham-Platinum (cCP)支架植入治疗。在血管内介入治疗前后记录有创主动脉压测量。结果:47例患者共植入48,8个zig型CP支架,其中bCP 24个,cCP 24个。CoA病变处平均主动脉直径(mm)由9.7±3.3 mm增加到19.2±2.9 mm (p p p p = 0.36)。结论:有创主动脉导管置入术证明血管内支架置入裸露或覆盖支架治疗CoA是有效的。
Evaluating the Effectiveness of Stenting for Aortic Coarctation.
Background: Coarctation of the aorta (CoA) is a congenital cardiovascular malformation involving narrowing of the thoracic aorta just distal to the left subclavian artery. The aim of our study was to evaluate the hemodynamic effects of endovascular treatment for CoA by using invasive aortic catheterization.
Methods: All patients with CoA who underwent treatment by aortic stent implantation between September 1, 2003, and February 1, 2019, at the "Onassis Cardiac Surgery Center," in Athens, Greece, were evaluated. Patients were treated with either bare (uncovered) Cheatham-Platinum (bCP) or covered Cheatham-Platinum (cCP) stent implantations. Invasive aortic pressure measurements were recorded before and after the endovascular intervention.
Results: A total of 48, eight zig CP stents, comprising 24 bCP and 24 cCP stents were implanted in 47 patients. The mean aortic diameter (mm) at the CoA lesion increased from 9.7 ± 3.3 to 19.2 ± 2.9 mm (p <0.01) after the endovascular procedure. The invasive mean blood pressure (BP; mm Hg) from catheterization in the descending aorta increased (before = 114.2 ± 12.8 vs. after = 135.5 ± 28.1; p <0.01), while the invasive mean BP (mm Hg) from catheterization in the ascending aorta was decreased (before = 156.8 ± 25.0 vs. after = 138.4 ± 27.5; p <0.01) after the intervention. The mean aortic BP gradient decreased in both types of stents after intervention (BP gradient among patients with cCP stents = 30.9 +/- 23.6 mmHg and BP gradient among patients with bCP stents = 38.0 +/-23.1 mmHg). However, there was no statistically significant difference between the two types of stents; p = 0.36.
Conclusions: Invasive aortic catheterization provided evidence that endovascular stenting with either bare or covered stents is efficient in treating patients with CoA.