妊娠早期每日产奶量的差异会改变奶牛的胎盘特征和新生儿代谢氨基酸水平。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2023-10-20 Epub Date: 2023-08-16 DOI:10.1262/jrd.2023-004
Riku Mashimo, Sayaka Ito, Chiho Kawashima
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引用次数: 0

摘要

我们研究了妊娠早期产奶量差异对足月胎盘特征、小牛出生体重及其代谢状态的影响。根据妊娠早期平均每日4%脂肪校正产奶量的四分位数,将34头荷斯坦奶牛分为三组(低,n=9;中,n=16;高,n=9)。妊娠早期和中期,高组的乳汁成分产量高于其他组(P<0.05)。虽然大多数胎盘特征在各组之间没有显著差异,但高组奶牛的单个子叶比低组大,中等大小的子叶更少(P<0.05)。低组和高组小牛的血浆氨基酸浓度显著高于中组小牛,尽管各组的小牛出生体重相似。此外,低组的奶牛比高组(P=0.004)和中组(P=0.058)的奶牛有更长的干旱期。这表明,由于泌乳量低和长时间干旱,低组奶牛可能为胎儿提供了更多的氨基酸。相反,高水平组的奶牛在妊娠早期需要更多的能量来哺乳,这会降低胎盘和胎儿的营养供应;然而,在妊娠后期增加单个子叶的大小可以确保向胎儿提供与低组奶牛相同数量的氨基酸,从而恢复出生体重。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Differences in daily milk production during early pregnancy alter placental characteristics and neonatal metabolic amino acid levels in dairy cows.

Differences in daily milk production during early pregnancy alter placental characteristics and neonatal metabolic amino acid levels in dairy cows.

Differences in daily milk production during early pregnancy alter placental characteristics and neonatal metabolic amino acid levels in dairy cows.

Differences in daily milk production during early pregnancy alter placental characteristics and neonatal metabolic amino acid levels in dairy cows.

We investigated the effects of differences in milk production during early pregnancy on placental characteristics at full term, calf birth weights, and their metabolic status. Thirty-four Holstein cows were categorized into three groups (Low, n = 9; Middle, n = 16; High, n = 9) based on the quartile of average daily 4% fat-corrected milk production during early pregnancy. The High group showed higher milk component production than the other groups (P < 0.05) during early and mid-pregnancy. Although most placental characteristics did not differ significantly among the groups, cows in the High group had larger individual cotyledons and fewer medium-sized cotyledons than those in the Low group (P < 0.05). Plasma amino acid concentrations of calves in the Low and High groups were significantly higher than those of calves in the Middle group, although calf birth weights were similar among the groups. Furthermore, cows in the Low group had longer dry periods than those in the High (P = 0.004) and Middle (P = 0.058) groups. This suggests that cows in the Low group may have provided more amino acids to the fetus because of low lactation and long dry periods. Conversely, cows in the High group required more energy for lactation during early pregnancy, which can reduce nutrient availability to the placenta and fetus; however, increasing individual cotyledonary sizes during late pregnancy may ensure that the same amounts of amino acids as those in cows in the Low group are supplied to the fetus, recovering the birth weights.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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