{"title":"埃塞俄比亚西北部Debre Tabor综合专科医院产前护理孕妇中HBV和HCV血清阳性率及相关因素:一项横断面研究","authors":"Ayenew Assefa, Teklehaimanot Kiros, Birtukan Delelegn","doi":"10.1155/2023/2282673","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Infections with the hepatitis B virus (HBV) and the hepatitis C virus (HCV) are worldwide problems that particularly place a heavy burden on developing nations. HBV and HCV infections during pregnancy have a high rate of vertical transmission and harmful consequences for both the mother and the child. Therefore, this study was carried out to assess the seroprevalence and associated factors of HBV and HCV infections among pregnant women attending antenatal care at Debre Tabor Comprehensive Specialized Hospital in Ethiopia.</p><p><strong>Methods: </strong>A cross-sectional study was conducted from March 15<sup>th</sup> to September 16<sup>th</sup>, 2022, at the Debre Tabor Comprehensive Specialized Hospital antenatal care clinic. Five milliliters of venous blood were collected from 422 pregnant women selected using a simple random sampling method. Data on sociodemographic characteristics and risk factors were collected using a prestructured questionnaire. A chi-square test, bivariate, and multivariate analyses were used to evaluate the association between dependent and independent variables. <i>p</i> values less than 0.05 were considered statistically significant.</p><p><strong>Results: </strong>The seroprevalence of HBV and HCV infections was found to be 13% and 0.5%, respectively. Undertaking blood transfusion (AOR = 14.2, CI = 5.81-34.526, <i>p</i> = 0.001), tattooing (AOR = 3.99, CI = 1.1-14.36, <i>p</i> = 0.034), and dental therapy (AOR = 4.9, CI = 1.41-17.025, <i>p</i> = 0.012) were significantly associated with HBV infection.</p><p><strong>Conclusion: </strong>HBV infection in pregnant women was shown to have a high endemicity (13%) in this investigation, whereas the seroprevalence of HCV infection was low (0.5%). HBV infection was significantly associated with a history of blood transfusions, tattooing, and dental therapy. Screening pregnant women for HBV and HCV infections and providing effective therapy would ensure better outcomes for the newborn. In addition, health education must be used to increase knowledge of screening and modes of transmission.</p>","PeriodicalId":14098,"journal":{"name":"International Journal of Microbiology","volume":null,"pages":null},"PeriodicalIF":2.8000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413223/pdf/","citationCount":"0","resultStr":"{\"title\":\"Seroprevalence and Associated Factors of HBV and HCV among Pregnant Women Attending Antenatal Care at Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia: A Cross-Sectional Study.\",\"authors\":\"Ayenew Assefa, Teklehaimanot Kiros, Birtukan Delelegn\",\"doi\":\"10.1155/2023/2282673\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Infections with the hepatitis B virus (HBV) and the hepatitis C virus (HCV) are worldwide problems that particularly place a heavy burden on developing nations. HBV and HCV infections during pregnancy have a high rate of vertical transmission and harmful consequences for both the mother and the child. Therefore, this study was carried out to assess the seroprevalence and associated factors of HBV and HCV infections among pregnant women attending antenatal care at Debre Tabor Comprehensive Specialized Hospital in Ethiopia.</p><p><strong>Methods: </strong>A cross-sectional study was conducted from March 15<sup>th</sup> to September 16<sup>th</sup>, 2022, at the Debre Tabor Comprehensive Specialized Hospital antenatal care clinic. Five milliliters of venous blood were collected from 422 pregnant women selected using a simple random sampling method. Data on sociodemographic characteristics and risk factors were collected using a prestructured questionnaire. A chi-square test, bivariate, and multivariate analyses were used to evaluate the association between dependent and independent variables. <i>p</i> values less than 0.05 were considered statistically significant.</p><p><strong>Results: </strong>The seroprevalence of HBV and HCV infections was found to be 13% and 0.5%, respectively. Undertaking blood transfusion (AOR = 14.2, CI = 5.81-34.526, <i>p</i> = 0.001), tattooing (AOR = 3.99, CI = 1.1-14.36, <i>p</i> = 0.034), and dental therapy (AOR = 4.9, CI = 1.41-17.025, <i>p</i> = 0.012) were significantly associated with HBV infection.</p><p><strong>Conclusion: </strong>HBV infection in pregnant women was shown to have a high endemicity (13%) in this investigation, whereas the seroprevalence of HCV infection was low (0.5%). HBV infection was significantly associated with a history of blood transfusions, tattooing, and dental therapy. Screening pregnant women for HBV and HCV infections and providing effective therapy would ensure better outcomes for the newborn. In addition, health education must be used to increase knowledge of screening and modes of transmission.</p>\",\"PeriodicalId\":14098,\"journal\":{\"name\":\"International Journal of Microbiology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10413223/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Microbiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/2023/2282673\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Microbiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2023/2282673","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
背景:乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)感染是世界性的问题，特别是对发展中国家造成沉重的负担。妊娠期乙型肝炎病毒和丙型肝炎病毒感染具有很高的垂直传播率，对母亲和孩子都有有害的后果。因此，本研究旨在评估在埃塞俄比亚Debre Tabor综合专科医院接受产前护理的孕妇中HBV和HCV感染的血清阳性率及其相关因素。方法:横断面研究于2022年3月15日至9月16日在Debre Tabor综合专科医院产前保健诊所进行。采用简单随机抽样法，抽取422例孕妇静脉血5毫升。社会人口学特征和危险因素的数据使用预先结构化的问卷收集。使用卡方检验、双变量和多变量分析来评估因变量和自变量之间的相关性。P值小于0.05认为有统计学意义。结果:血清HBV和HCV感染率分别为13%和0.5%。接受输血(AOR = 14.2, CI = 5.81 ~ 34.526, p = 0.001)、纹身(AOR = 3.99, CI = 1.1 ~ 14.36, p = 0.034)和牙科治疗(AOR = 4.9, CI = 1.41 ~ 17.025, p = 0.012)与HBV感染显著相关。结论:本次调查显示，HBV感染在孕妇中具有较高的地方性(13%)，而HCV感染的血清患病率较低(0.5%)。HBV感染与输血史、文身史和牙科治疗史显著相关。对孕妇进行HBV和HCV感染筛查并提供有效治疗将确保新生儿获得更好的结局。此外，必须利用健康教育提高对筛查和传播方式的认识。
Seroprevalence and Associated Factors of HBV and HCV among Pregnant Women Attending Antenatal Care at Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia: A Cross-Sectional Study.
Background: Infections with the hepatitis B virus (HBV) and the hepatitis C virus (HCV) are worldwide problems that particularly place a heavy burden on developing nations. HBV and HCV infections during pregnancy have a high rate of vertical transmission and harmful consequences for both the mother and the child. Therefore, this study was carried out to assess the seroprevalence and associated factors of HBV and HCV infections among pregnant women attending antenatal care at Debre Tabor Comprehensive Specialized Hospital in Ethiopia.
Methods: A cross-sectional study was conducted from March 15th to September 16th, 2022, at the Debre Tabor Comprehensive Specialized Hospital antenatal care clinic. Five milliliters of venous blood were collected from 422 pregnant women selected using a simple random sampling method. Data on sociodemographic characteristics and risk factors were collected using a prestructured questionnaire. A chi-square test, bivariate, and multivariate analyses were used to evaluate the association between dependent and independent variables. p values less than 0.05 were considered statistically significant.
Results: The seroprevalence of HBV and HCV infections was found to be 13% and 0.5%, respectively. Undertaking blood transfusion (AOR = 14.2, CI = 5.81-34.526, p = 0.001), tattooing (AOR = 3.99, CI = 1.1-14.36, p = 0.034), and dental therapy (AOR = 4.9, CI = 1.41-17.025, p = 0.012) were significantly associated with HBV infection.
Conclusion: HBV infection in pregnant women was shown to have a high endemicity (13%) in this investigation, whereas the seroprevalence of HCV infection was low (0.5%). HBV infection was significantly associated with a history of blood transfusions, tattooing, and dental therapy. Screening pregnant women for HBV and HCV infections and providing effective therapy would ensure better outcomes for the newborn. In addition, health education must be used to increase knowledge of screening and modes of transmission.
期刊介绍：
International Journal of Microbiology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies on microorganisms and their interaction with hosts and the environment. The journal covers all microbes, including bacteria, fungi, viruses, archaea, and protozoa. Basic science will be considered, as well as medical and applied research.
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