[1例婴儿复发性肺不张:新生儿囊性纤维化筛查假阴性1例]。

Q3 Medicine
Revue medicale de Liege Pub Date : 2023-07-01
Matthieu Thimmesch, David Tuerlinckx, Marie Habay, Patrick Lebecque
{"title":"[1例婴儿复发性肺不张:新生儿囊性纤维化筛查假阴性1例]。","authors":"Matthieu Thimmesch,&nbsp;David Tuerlinckx,&nbsp;Marie Habay,&nbsp;Patrick Lebecque","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>In infants as well as in older children, persistent or recurrent atelectasis remains a classic indication for sweat testing, even if neonatal screening for cystic fibrosis has been considered normal. Atelectasis is a common complication of cystic fibrosis. Yet, it has rarely been reported in infants. In cystic fibrosis, chronic atelectasis worsens the prognosis, especially when involving a lower lobe. Therefore, early and effective intervention is required. Antibiotic therapy, intensive chest physiotherapy together with inhaled mucolytics often allow to relieve bronchial obstruction but bronchoscopy with local aspiration and Dornase alpha instillation is sometimes necessary. In a two-month-old infant, we describe here the first reported case of false-negative cystic fibrosis newborn screening in Belgium.</p>","PeriodicalId":21414,"journal":{"name":"Revue medicale de Liege","volume":"78 7-8","pages":"436-440"},"PeriodicalIF":0.0000,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Recurrent atelectasis in an infant : about one case of false-negative newborn screening for cystic fibrosis].\",\"authors\":\"Matthieu Thimmesch,&nbsp;David Tuerlinckx,&nbsp;Marie Habay,&nbsp;Patrick Lebecque\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In infants as well as in older children, persistent or recurrent atelectasis remains a classic indication for sweat testing, even if neonatal screening for cystic fibrosis has been considered normal. Atelectasis is a common complication of cystic fibrosis. Yet, it has rarely been reported in infants. In cystic fibrosis, chronic atelectasis worsens the prognosis, especially when involving a lower lobe. Therefore, early and effective intervention is required. Antibiotic therapy, intensive chest physiotherapy together with inhaled mucolytics often allow to relieve bronchial obstruction but bronchoscopy with local aspiration and Dornase alpha instillation is sometimes necessary. In a two-month-old infant, we describe here the first reported case of false-negative cystic fibrosis newborn screening in Belgium.</p>\",\"PeriodicalId\":21414,\"journal\":{\"name\":\"Revue medicale de Liege\",\"volume\":\"78 7-8\",\"pages\":\"436-440\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revue medicale de Liege\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revue medicale de Liege","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

摘要

在婴儿和年龄较大的儿童中,即使新生儿囊性纤维化筛查被认为是正常的,持续性或复发性肺不张仍然是汗液检测的典型适应症。肺不张是囊性纤维化的常见并发症。然而,在婴儿中很少有报道。在囊性纤维化中,慢性肺不张恶化预后,尤其是累及下肺叶时。因此,需要早期有效的干预。抗生素治疗,强化胸部物理治疗和吸入黏液解药通常可以缓解支气管阻塞,但有时需要支气管镜局部吸入和Dornase - α滴注。在一个两个月大的婴儿,我们在这里描述假阴性囊性纤维化新生儿筛查在比利时的第一例报告。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Recurrent atelectasis in an infant : about one case of false-negative newborn screening for cystic fibrosis].

In infants as well as in older children, persistent or recurrent atelectasis remains a classic indication for sweat testing, even if neonatal screening for cystic fibrosis has been considered normal. Atelectasis is a common complication of cystic fibrosis. Yet, it has rarely been reported in infants. In cystic fibrosis, chronic atelectasis worsens the prognosis, especially when involving a lower lobe. Therefore, early and effective intervention is required. Antibiotic therapy, intensive chest physiotherapy together with inhaled mucolytics often allow to relieve bronchial obstruction but bronchoscopy with local aspiration and Dornase alpha instillation is sometimes necessary. In a two-month-old infant, we describe here the first reported case of false-negative cystic fibrosis newborn screening in Belgium.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Revue medicale de Liege
Revue medicale de Liege Medicine-Medicine (all)
CiteScore
0.80
自引率
0.00%
发文量
0
期刊介绍: The Medical Review of Liege is a tool for continuous medical training being addressed to students, general practitioners, and specialists
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信