18F-氟胆碱PET/CT诊断子宫内膜异位症患者的肝细胞癌双侧卵巢转移。

IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Nuclear Medicine and Molecular Imaging Pub Date : 2023-10-01 Epub Date: 2023-04-14 DOI:10.1007/s13139-023-00796-4

Adrien Latgé, Gerlinde Averous, Anne Gressel, François Faitot, Benjamin Leroy-Freschini

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引用次数: 0

摘要

一名有肝细胞癌病史的47岁女性因甲胎蛋白升高而被转诊接受18F-氟胆碱PET/CT评估。检查显示有几个腹膜吸收和两个结节性盆腔病灶。胸腔镜检查可以确认和切除肝细胞癌的多个腹膜转移，而盆腔活检显示子宫内膜异位症和血管内瘤。然而，甲胎蛋白持续上升：随后的18F-氟脱氧葡萄糖PET/CT检查未发现盆腔摄取，而18F-氟胆碱PET/CT显示两个盆腔肿块中有强烈的示踪剂积聚，对应于肝细胞癌的双侧卵巢转移。我们强调了18F-氟胆碱PET/CT在肝细胞癌中的重要性，尤其是在患有子宫内膜异位症等混杂合并症的患者中。

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Bilateral Ovarian Metastases of Hepatocellular Carcinoma Diagnosed with ¹⁸F-Fluorocholine PET/CT in a Patient with Endometriosis.

A 47-year-old woman with history of hepatocellular carcinoma was referred for ¹⁸F-fluorocholine PET/CT evaluation due to elevated alpha-fetoprotein. The examination showed several peritoneal uptakes and two nodular pelvic foci. Coelioscopic exploration allowed confirmation and resection of multiple peritoneal metastases from hepatocellular carcinoma while pelvic biopsies revealed endometriosis and endosalpingiosis. However, alpha-fetoprotein kept rising: subsequent ¹⁸F-fluorodesoxyglucose PET/CT exploration found no pelvic uptake, while ¹⁸F-fluorocholine PET/CT revealed intense tracer accumulation in the two pelvic masses corresponding to bilateral ovarian metastases of hepatocellular carcinoma. We highlight the importance of ¹⁸F-fluorocholine PET/CT in hepatocellular carcinoma especially in patients with confounding comorbidities such as endometriosis.

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来源期刊

Nuclear Medicine and Molecular Imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

2.20

自引率

7.70%

发文量

期刊介绍： Nuclear Medicine and Molecular Imaging (Nucl Med Mol Imaging) is an official journal of the Korean Society of Nuclear Medicine, which bimonthly publishes papers on February, April, June, August, October, and December about nuclear medicine and related sciences such as radiochemistry, radiopharmacy, dosimetry and pharmacokinetics / pharmacodynamics of radiopharmaceuticals, nuclear and molecular imaging analysis, nuclear and molecular imaging instrumentation, radiation biology and radionuclide therapy. The journal specially welcomes works of artificial intelligence applied to nuclear medicine. The journal will also welcome original works relating to molecular imaging research such as the development of molecular imaging probes, reporter imaging assays, imaging cell trafficking, imaging endo(exo)genous gene expression, and imaging signal transduction. Nucl Med Mol Imaging publishes the following types of papers: original articles, reviews, case reports, editorials, interesting images, and letters to the editor. The Korean Society of Nuclear Medicine (KSNM) KSNM is a scientific and professional organization founded in 1961 and a member of the Korean Academy of Medical Sciences of the Korean Medical Association which was established by The Medical Services Law. The aims of KSNM are the promotion of nuclear medicine and cooperation of each member. The business of KSNM includes holding academic meetings and symposia, the publication of journals and books, planning and research of promoting science and health, and training and qualification of nuclear medicine specialists.