[在Côte科特迪瓦阿比让心脏病研究所,缺血性心脏病患者的心率恢复情况和冠状动脉病变情况]。

Iklo Coulibaly, Bénédicte Boka, Hermann Yao, Arnaud Ekou, Gabin Tro, Camille Toure, Désirée Kouassi
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引用次数: 0

摘要

在压力测试中测量心率恢复(HRR),评估迷走-交感神经平衡。它是已知的心血管死亡率的预后和预测参数,被认为与冠状动脉疾病的存在和严重程度相关。这项工作的目的是评估心率恢复在诊断和冠状动脉病变严重程度的预测价值在撒哈拉以南非洲的一个主要大都市,在那里获得专科护理是不均匀分布的。患者和方法:我们于2010年1月至2020年2月在阿比让心脏病研究所进行了一项回顾性观察研究,包括在运动试验阳性后进行诊断性冠状动脉造影的患者。分析并比较心率恢复异常患者与正常患者的临床、血管造影及运动参数。结果:主要的研究局限是样本量小,因为血管造影的成本限制了它的实现。我们记录了41例患者,平均年龄53.4±9.6岁,男性为主(性别比3.6)。主要年龄组在50至60岁之间。男性年龄大于女性,差异无统计学意义。主要的心血管危险因素为超重/肥胖(68.29%)和高血压(61%)。8例(19.5%)HRR异常(≤12 bpm)患者冠脉病变较明显(p=0.02),较严重(p=0.003)。HRR异常患者年龄偏大(p=0.081),变时储备和最大心率较低(p=0.008和p=0.042),差异无统计学意义(p=0.081)。HHR阳性预测值为87.5%,阴性预测值为60.6%。结论:HRR异常可预测冠心病的存在及其严重程度。在资源有限的国家,评估压力测试期间的HRR有助于发现、评估和监测缺血性心脏病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Heart rate recovery and presence of coronary lesions in case of ischemic heart disease at the Abidjan Cardiology Institute in Côte d'Ivoire].

Introduction: Heart rate recovery (HRR) measured during stress tests, assesses the vago-sympathetic balance. It is a known prognostic and predictive parameter of cardiovascular mortality that is believed to be correlated with the presence and severity of coronary artery disease. The aim of this work was to assess the predictive value of heart rate recovery in the diagnostic and severity of coronary lesions in a major metropolis of sub-Saharan Africa where access to specialist care is unevenly distributed.

Patients and method: We conducted a retrospective observational study from January 2010 to February 2020 at the Abidjan Cardiology Institute, including patients who performed a diagnostic coronary angiography after a positive exercise test. Clinical, angiographic and exercise parameters were analyzed and compared in patients with abnormal heart rate recovery (HRR) and those with normal one.

Results: The main study limitation is small sampling due to the cost of the angiographic procedure which limits its realization. We recorded 41 subjects whose mean age was 53.4 ± 9.6 years with a male predominance (sex ratio of 3.6). The predominant age group was between 50 and 60 years. Males were older than females with no significant difference. The predominant cardiovascular risk factors were overweight/obesity (68.29%) and hypertension (61%). Eight patients (19.5%) presenting an abnormal HRR (≤12 bpm) had more significant coronary disease (p=0.02) and more severe ones (p=0.003). Patients with abnormal HRR tended to be older without statistical significance (p=0.081), and had lower chronotropic reserve and maximum heart rate (p=0.008 and p=0.042, respectively). The positive predictive value of HHR was 87.5% and its negative predictive value was 60.6%.

Conclusion: Abnormal HRR can predict the presence of coronary artery disease and its severity. Evaluating HRR during stress tests could help in the detection, evaluation, and monitoring of ischemic heart disease in our resource-limited countries.

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