Teja Yeramosu, Jacob Wait, Stephen L Kates, Gregory J Golladay, Nirav K Patel, Jibanananda Satpathy
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After splitting the data into training (75%) and validation (25%) data sets, various machine learning models were used to predict non-home discharge. The model with the best area under the curve (AUC) was further assessed to identify the most important variables.</p><p><strong>Results: </strong>In total, 19,840 geriatric patients undergoing THA were included in the final analyses, of which 5194 (26.2%) were discharged to a non-home setting. The RF model performed the best and identified age above 78 years (OR: 1.08 [1.07, 1.09], <i>P</i> < .0001), as the most important variable when predicting non-home discharge in geriatric patients with THA, followed by severe American Society of Anesthesiologists grade (OR: 1.94 [1.80, 2.10], <i>P</i> < .0001), operation time (OR: 1.01 [1.00, 1.02], <i>P</i> < .0001), anemia (OR: 2.20 [1.87, 2.58], <i>P</i> < .0001), and general anesthesia (OR: 1.64 [1.52, 1.79], <i>P</i> < .0001). Each of these variables was also significant in MLR analysis. The RF model displayed good discrimination with AUC = .831.</p><p><strong>Discussion: </strong>The RF model revealed clinically important variables for assessing discharge disposition in geriatric patients undergoing THA, with the five most important factors being older age, severe ASA grade, longer operation time, anemia, and general anesthesia.</p><p><strong>Conclusions: </strong>With the rising emphasis on patient-centered care, incorporating models such as these may allow for preoperative risk factor mitigation and reductions in healthcare expenditure.</p>","PeriodicalId":48568,"journal":{"name":"Geriatric Orthopaedic Surgery & Rehabilitation","volume":"14 ","pages":"21514593231179316"},"PeriodicalIF":1.6000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0a/f0/10.1177_21514593231179316.PMC10225957.pdf","citationCount":"0","resultStr":"{\"title\":\"Prediction of Non-Home Discharge Following Total Hip Arthroplasty in Geriatric Patients.\",\"authors\":\"Teja Yeramosu, Jacob Wait, Stephen L Kates, Gregory J Golladay, Nirav K Patel, Jibanananda Satpathy\",\"doi\":\"10.1177/21514593231179316\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>The majority of total hip arthroplasty (THA) patients are discharged home postoperatively, however, many still require continued medical care. We aimed to identify important characteristics that predict nonhome discharge in geriatric patients undergoing THA using machine learning. We hypothesize that our analyses will identify variables associated with decreased functional status and overall health to be predictive of non-home discharge.</p><p><strong>Materials and methods: </strong>Elective, unilateral, THA patients above 65 years of age were isolated in the NSQIP database from 2018-2020. Demographic, pre-operative, and intraoperative variables were analyzed. After splitting the data into training (75%) and validation (25%) data sets, various machine learning models were used to predict non-home discharge. The model with the best area under the curve (AUC) was further assessed to identify the most important variables.</p><p><strong>Results: </strong>In total, 19,840 geriatric patients undergoing THA were included in the final analyses, of which 5194 (26.2%) were discharged to a non-home setting. 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引用次数: 0
摘要
导读:大多数全髋关节置换术(THA)患者术后出院回家,然而,许多仍然需要继续医疗护理。我们的目的是利用机器学习确定预测老年THA患者非家庭出院的重要特征。我们假设,我们的分析将识别与功能状态下降和整体健康相关的变量,以预测非家庭出院。材料与方法:从2018-2020年NSQIP数据库中分离出65岁以上的选择性、单侧、THA患者。对人口统计学、术前和术中变量进行分析。在将数据分成训练(75%)和验证(25%)数据集后,使用各种机器学习模型来预测非家庭出院。进一步评估曲线下面积(AUC)最佳的模型,以确定最重要的变量。结果:总共有19840例接受THA的老年患者被纳入最终分析,其中5194例(26.2%)出院到非家庭环境。RF模型表现最好,年龄大于78岁(OR: 1.08 [1.07, 1.09], P < 0.0001)是预测老年THA患者非居家出院的最重要变量,其次是美国麻醉医师学会重度分级(OR: 1.94 [1.80, 2.10], P < 0.0001)、手术时间(OR: 1.01 [1.00, 1.02], P < 0.0001)、贫血(OR: 2.20 [1.87, 2.58], P < 0.0001)和全身麻醉(OR: 1.64 [1.52, 1.79], P < 0.0001)。这些变量在MLR分析中也具有显著性。RF模型具有较好的识别效果,AUC = 0.831。讨论:RF模型揭示了评估老年THA患者出院处置的临床重要变量,其中最重要的五个因素是年龄较大、ASA严重等级、手术时间较长、贫血和全身麻醉。结论:随着对以患者为中心的护理的日益重视,纳入这些模型可能允许术前风险因素的缓解和医疗保健支出的减少。
Prediction of Non-Home Discharge Following Total Hip Arthroplasty in Geriatric Patients.
Introduction: The majority of total hip arthroplasty (THA) patients are discharged home postoperatively, however, many still require continued medical care. We aimed to identify important characteristics that predict nonhome discharge in geriatric patients undergoing THA using machine learning. We hypothesize that our analyses will identify variables associated with decreased functional status and overall health to be predictive of non-home discharge.
Materials and methods: Elective, unilateral, THA patients above 65 years of age were isolated in the NSQIP database from 2018-2020. Demographic, pre-operative, and intraoperative variables were analyzed. After splitting the data into training (75%) and validation (25%) data sets, various machine learning models were used to predict non-home discharge. The model with the best area under the curve (AUC) was further assessed to identify the most important variables.
Results: In total, 19,840 geriatric patients undergoing THA were included in the final analyses, of which 5194 (26.2%) were discharged to a non-home setting. The RF model performed the best and identified age above 78 years (OR: 1.08 [1.07, 1.09], P < .0001), as the most important variable when predicting non-home discharge in geriatric patients with THA, followed by severe American Society of Anesthesiologists grade (OR: 1.94 [1.80, 2.10], P < .0001), operation time (OR: 1.01 [1.00, 1.02], P < .0001), anemia (OR: 2.20 [1.87, 2.58], P < .0001), and general anesthesia (OR: 1.64 [1.52, 1.79], P < .0001). Each of these variables was also significant in MLR analysis. The RF model displayed good discrimination with AUC = .831.
Discussion: The RF model revealed clinically important variables for assessing discharge disposition in geriatric patients undergoing THA, with the five most important factors being older age, severe ASA grade, longer operation time, anemia, and general anesthesia.
Conclusions: With the rising emphasis on patient-centered care, incorporating models such as these may allow for preoperative risk factor mitigation and reductions in healthcare expenditure.
期刊介绍:
Geriatric Orthopaedic Surgery & Rehabilitation (GOS) is an open access, peer-reviewed journal that provides clinical information concerning musculoskeletal conditions affecting the aging population. GOS focuses on care of geriatric orthopaedic patients and their subsequent rehabilitation. This journal is a member of the Committee on Publication Ethics (COPE).