使用人体测量指标评估癌症儿童幸存者皮质骨的质量和数量。

IF 1.6 3区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE
Oral Radiology Pub Date : 2023-10-01 Epub Date: 2023-07-20 DOI:10.1007/s11282-023-00700-y
Kyriaki Seremidi, Anastasia Mitsea, William Papaioannou, Konstantina Petroleka, Sotiria Gizani
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引用次数: 0

摘要

目的:评估儿童癌症幸存者(CCS)的下颌骨皮质骨,并将其与疾病和治疗特征相关联。方法:由两名独立观察者对60名CCS和120名年龄和性别匹配的健康人的牙齿全景照片进行评估。骨被分为正常、中度或重度侵蚀,并在双侧四个部位计算其宽度。使用卡方和皮尔逊相关系数检验显著差异。通过多元回归分析检测可能的危险因素。结果:45%的CCS有中度骨质侵蚀,而67%的健康人骨骼正常。CCS的平均宽度为3.9毫米(1.9毫米-6.4毫米),健康对照组为2.7毫米(1.4毫米-6毫米)。上述差异均无显著性。在较年轻的时候被诊断出的幸存者出现轻度骨质侵蚀的可能性高出五倍。结论:目前的研究没有证明抗肿瘤治疗对皮质骨的直接作用,因此需要进行更精心设计的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Assessing quality and quantity of cortical bone in childhood cancer survivors using anthropometric indices.

Assessing quality and quantity of cortical bone in childhood cancer survivors using anthropometric indices.

Objectives: Evaluate mandibular cortical bone in childhood cancer survivors (CCS) and correlate findings with disease and treatment characteristics.

Methods: Dental panoramic radiographs of 60 CCS and of 120 age and gender-matched healthy individuals were assessed by two independent observers. Bone was categorized as normal, moderately or severely eroded and its width was calculated at four sites bilaterally. Significant differences were tested using Chi-square and Pearson correlation co-efficient. Possible risk factors were detected by multivariate regression analysis.

Results: Forty five percent of CCS had moderately eroded bone, while 67% of healthy individuals normal bone. Mean width was 3.9 mm in CCS (1.9 mm-6.4 mm) and 2.7 mm in healthy controls (1.4 mm-6 mm). None of the above differences were significant. Survivors diagnosed at a younger age had a five times greater probability of presenting mildly eroded bone.

Conclusions: No direct effect of antineoplastic treatment on cortical bone could be demonstrated in the current study, underlying the need for more well-designed studies.

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来源期刊
Oral Radiology
Oral Radiology DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
4.20
自引率
13.60%
发文量
87
审稿时长
>12 weeks
期刊介绍: As the official English-language journal of the Japanese Society for Oral and Maxillofacial Radiology and the Asian Academy of Oral and Maxillofacial Radiology, Oral Radiology is intended to be a forum for international collaboration in head and neck diagnostic imaging and all related fields. Oral Radiology features cutting-edge research papers, review articles, case reports, and technical notes from both the clinical and experimental fields. As membership in the Society is not a prerequisite, contributions are welcome from researchers and clinicians worldwide.
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