变性成人的银屑病患病率及与激素治疗的关系。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
ACS Applied Bio Materials Pub Date : 2023-07-28 eCollection Date: 2023-08-01 DOI:10.1089/trgh.2021.0104
Hayley Braun, Elaine C Thompson, Qi Zhang, Vin Tangpricha, Michael Goodman, Howa Yeung
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引用次数: 0

摘要

目的:激素疗法(HT)在跨性别人群银屑病的病因和发展中的作用尚不清楚:方法:通过对 696 名跨性别者进行横断面调查,研究跨男性化(TM)和跨女性化(TF)成年人的银屑病患病率,以及银屑病与性别确认 HT 之间的关系:有 17 名变性人(4.9%;95% 置信区间 [CI]:2.6-7.2)和 13 名变性人(3.7%;95% 置信区间:1.7-5.7)曾被诊断出患有银屑病。目前患有银屑病的 TM 患者为 2.6%(95% 置信区间:0.9-4.3),TF 患者为 1.1%(95% 置信区间:0.03-2.3)。值得注意的是,在曾经患有银屑病的参与者中,17%的人认为其银屑病与性别认同 HT 之间存在联系:结论:变性人的银屑病发病率与普通人群的估计值相似。银屑病及其严重程度与性别认同 HT 之间的潜在关联值得进一步开展纵向研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence of Psoriasis and Perceived Association with Hormone Therapy in Transgender Adults.

Purpose: The role of hormone therapy (HT) in the etiology and progression of psoriasis in the transgender population is unclear.

Methods: The prevalence of psoriasis in transmasculine (TM) and transfeminine (TF) adults and perceived links between psoriasis and gender-affirming HT is examined using a cross-sectional survey of 696 transgender individuals.

Results: Ever diagnosis of psoriasis was reported by 17 TM persons (4.9%; 95% confidence interval [CI]: 2.6-7.2) and 13 TF persons (3.7%; 95% CI: 1.7-5.7). Prevalence of current psoriasis in TM persons was 2.6% (95% CI: 0.9-4.3) and 1.1% (95% CI: 0.03-2.3) among TF persons. Notably, among participants who had ever had psoriasis, 17% perceived a link between their psoriasis and gender-affirming HT.

Conclusions: Prevalence of psoriasis among transgender persons resembled estimates in the general population. Potential associations between psoriasis and its severity with gender-affirming HT warrant further longitudinal research.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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