Ana I. Soza-Bolaños DDS, Endod, Rubén A. Domínguez-Pérez DDS, MSc, Endod, PhD, José L. Ayala-Herrera DDS, MSc, PhD, Rosa M. Pérez-Serrano PhD, Uriel Soto-Barreras DDS, MSc, PhD, León F. Espinosa-Cristóbal DDS, MSc, PhD, Claudia A. Rivera-Albarrán DDS, MSc, PhD, Guadalupe Zaldívar-Lelo de Larrea MD, MSc, PhD
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Presence of methanogenic archaea in necrotic root canals of patients with or without type 2 diabetes mellitus
Theoretically, a necrotic root canal fulfils all requirements as a niche for methanogens to inhabit. However, their presence in it and its implication in apical periodontitis (AP) is controversial. Therefore, to contribute to ending the controversy, this study aimed to detect and compare methanogens' presence in two distinct niches with supposedly different microenvironments; both were necrotic root canals associated with AP but one from patients with type 2 diabetes mellitus (T2DM) while the other from non-diabetic patients. A clinical examination was performed on 65 T2DM patients and 73 non-diabetic controls. Samples from necrotic root canals were obtained, and methanogens were identified. The presence of methanogens was three times higher (27.6%) in the T2DM group than in non-diabetic patients (8.2%). In addition, methanogens' presence was associated with a higher prevalence of periapical symptoms.
期刊介绍：
The Australian Endodontic Journal provides a forum for communication in the different fields that encompass endodontics for all specialists and dentists with an interest in the morphology, physiology, and pathology of the human tooth, in particular the dental pulp, root and peri-radicular tissues.
The Journal features regular clinical updates, research reports and case reports from authors worldwide, and also publishes meeting abstracts, society news and historical endodontic glimpses.
The Australian Endodontic Journal is a publication for dentists in general and specialist practice devoted solely to endodontics. It aims to promote communication in the different fields that encompass endodontics for those dentists who have a special interest in endodontics.
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