Beatriz Atonal-Flores, María de la Luz León-Vázquez, Armando Barranco-Juarez
{"title":"[利拉鲁肽、西格列汀/二甲双胍、利格列汀、西格列汀治疗后糖尿病的指标]。","authors":"Beatriz Atonal-Flores, María de la Luz León-Vázquez, Armando Barranco-Juarez","doi":"10.5281/zenodo.8200442","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The control of diabetes mellitus is multifactorial, the different therapeutic options make it necessary to compare the effectiveness with previous therapeutic schemes.</p><p><strong>Objective: </strong>Analize the indicators of control of diabetes mellitus after incorporating liraglutide, sitagliptin/metformin, linagliptin, and sitagliptin.</p><p><strong>Methods: </strong>Observational, analytical, longitudinal study. Glucose, glycosylated hemoglobin, and blood pressure were compared after the inclusion of new cues in patients with diabetes mellitus; in addition to the control indicators reported in the unit in october, november, and december 2000, with those of 2021 in the same months. A descriptive analysis was performed, T for related samples and McNemar, a value of < .05 was considered significant, a confidence level of 95%, with the IBM-SPSS 24 software.</p><p><strong>Results: </strong>352 files were analyzed, 59% women, aged 26 to 88 years, and the percentage of control decreased after the change of scheme (38.4% vs 35.8%) without a statistical difference (p .503). There was no statistical difference between the levels of glucose, glycated hemoglobin, weight, and blood pressure before and six months after the change. In the unit, the regimen glycemic control indicator improved in October, November, and December 2020 compared to the same months in 2021, it increased (from 17.2, 18.7, and 16.3, to 41.6, 47.2, and 46.5%). Blood pressure control went from 64.5, 66.7, and 67 to 82.4, 85.1, and 83.1%.</p><p><strong>Conclusions: </strong>The control indicators in the unit improved, however, the patients who used the new keys did not show any difference.</p>","PeriodicalId":21419,"journal":{"name":"Revista médica del Instituto Mexicano del Seguro Social","volume":"61 4","pages":"489-495"},"PeriodicalIF":0.0000,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8a/50/04435117-61-4-489.PMC10484544.pdf","citationCount":"0","resultStr":"{\"title\":\"[Indicators of diabetes mellitus after liraglutide, sitagliptin/metformin, linagliptin, and sitagliptin].\",\"authors\":\"Beatriz Atonal-Flores, María de la Luz León-Vázquez, Armando Barranco-Juarez\",\"doi\":\"10.5281/zenodo.8200442\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>The control of diabetes mellitus is multifactorial, the different therapeutic options make it necessary to compare the effectiveness with previous therapeutic schemes.</p><p><strong>Objective: </strong>Analize the indicators of control of diabetes mellitus after incorporating liraglutide, sitagliptin/metformin, linagliptin, and sitagliptin.</p><p><strong>Methods: </strong>Observational, analytical, longitudinal study. Glucose, glycosylated hemoglobin, and blood pressure were compared after the inclusion of new cues in patients with diabetes mellitus; in addition to the control indicators reported in the unit in october, november, and december 2000, with those of 2021 in the same months. A descriptive analysis was performed, T for related samples and McNemar, a value of < .05 was considered significant, a confidence level of 95%, with the IBM-SPSS 24 software.</p><p><strong>Results: </strong>352 files were analyzed, 59% women, aged 26 to 88 years, and the percentage of control decreased after the change of scheme (38.4% vs 35.8%) without a statistical difference (p .503). There was no statistical difference between the levels of glucose, glycated hemoglobin, weight, and blood pressure before and six months after the change. In the unit, the regimen glycemic control indicator improved in October, November, and December 2020 compared to the same months in 2021, it increased (from 17.2, 18.7, and 16.3, to 41.6, 47.2, and 46.5%). 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引用次数: 0
摘要
背景:糖尿病的控制是多因素的,不同的治疗方案使得有必要与以往的治疗方案进行疗效比较。目的:分析利拉鲁肽、西格列汀/二甲双胍、利格列汀、西格列汀联合用药后糖尿病的控制指标。方法:观察性、分析性、纵向研究。比较糖尿病患者纳入新线索后的血糖、糖化血红蛋白和血压;除2000年10月、11月和12月在该单位报告的控制指标外,2021年的控制指标也在同一月份报告。采用IBM-SPSS 24软件进行描述性分析,T为相关样本和McNemar,值< 0.05认为显著,置信水平为95%。结果:共分析352份,女性59%,年龄26 ~ 88岁,方案改变后控制率下降(38.4% vs 35.8%),差异无统计学意义(p .503)。改变前后6个月的血糖、糖化血红蛋白、体重和血压水平无统计学差异。在该单元,2020年10月、11月、12月方案血糖控制指标较2021年同期有所改善(从17.2、18.7、16.3上升到41.6、47.2、46.5%)。血压控制从64.5、66.7和67上升到82.4、85.1和83.1%。结论:科室各项控制指标均有改善,但使用新钥匙的患者无明显差异。
[Indicators of diabetes mellitus after liraglutide, sitagliptin/metformin, linagliptin, and sitagliptin].
Background: The control of diabetes mellitus is multifactorial, the different therapeutic options make it necessary to compare the effectiveness with previous therapeutic schemes.
Objective: Analize the indicators of control of diabetes mellitus after incorporating liraglutide, sitagliptin/metformin, linagliptin, and sitagliptin.
Methods: Observational, analytical, longitudinal study. Glucose, glycosylated hemoglobin, and blood pressure were compared after the inclusion of new cues in patients with diabetes mellitus; in addition to the control indicators reported in the unit in october, november, and december 2000, with those of 2021 in the same months. A descriptive analysis was performed, T for related samples and McNemar, a value of < .05 was considered significant, a confidence level of 95%, with the IBM-SPSS 24 software.
Results: 352 files were analyzed, 59% women, aged 26 to 88 years, and the percentage of control decreased after the change of scheme (38.4% vs 35.8%) without a statistical difference (p .503). There was no statistical difference between the levels of glucose, glycated hemoglobin, weight, and blood pressure before and six months after the change. In the unit, the regimen glycemic control indicator improved in October, November, and December 2020 compared to the same months in 2021, it increased (from 17.2, 18.7, and 16.3, to 41.6, 47.2, and 46.5%). Blood pressure control went from 64.5, 66.7, and 67 to 82.4, 85.1, and 83.1%.
Conclusions: The control indicators in the unit improved, however, the patients who used the new keys did not show any difference.