银屑病关节炎的轴性受累:临床和放射学横断面研究

IF 1.2 Q4 RHEUMATOLOGY
Noha A Elsawy, Shaimaa E Farahat, Mohamed M El Shafei, Rehab Elnemr
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引用次数: 0

摘要

研究目的本研究旨在通过临床和影像学方法调查银屑病关节炎(PsA)患者的脊柱受累情况:方法:对根据 CASPAR 标准确诊的 50 名 PsA 患者进行了横断面临床研究。进行了临床检查和功能评估。结果:在 50 名 PsA 患者(平均年龄为 40 岁)中,有 1 名患者(平均年龄为 60 岁)患有脊柱炎:在 50 名 PsA 患者(平均年龄为 45.50 ± 9.90 岁)中(男性和女性分别占 27 人(54.0%)和 23 人(46.0%)),76% 的患者有放射性轴向受累;(26%)有炎性轴向疼痛,(50%)无炎性轴向疼痛(亚临床)。发现了三种轴向影像学模式,包括无骶髂关节炎的脊柱炎(15.78%)、有骶髂关节炎的脊柱炎(78.94%)和无脊柱炎的骶髂关节炎(5.26%)。在轴性 PsA 患者中,男性患者多于女性(χ2=11.679,P = 0.003),年龄较大(H = 15.817,P < 0.001),体重指数(BMI)较高(F = 5.145,P = 0.010),银屑病持续时间(H = 9.826,p = 0.007)和严重程度(Η=25.171,p < 0.001)增加,脊柱活动受限程度高于无轴向受累的 PsA 患者(F = 26.568,p < 0.001)。颈椎受累程度高于腰椎受累程度。PsA脊柱炎放射学指数评估的轴向放射学严重程度与健康评估问卷评估的残疾程度增加(rs = 0.533,p = 0.001)和短表-36评分评估的生活质量下降(rs = -0.321,p = 0.050)相关:这项研究表明,PsA 患者中轴受累的比例很高,其中有很高比例的患者无症状放射学发现。与腰椎相比,颈椎受累更频繁、更严重。轴型 PsA 男性多于女性,且具有年龄大、体重指数(BMI)高、银屑病病程长、脊柱活动受限等特点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Axial Involvement in Psoriatic Arthritis: A Cross-sectional Clinical and Radiologic Studies.

Objective: This study aimed to investigate spinal involvement in psoriatic arthritis (PsA) patients using clinical and radiographic methods.

Methods: A cross-sectional clinical study was conducted on 50 PsA patients diagnosed according to the CASPAR criteria. Clinical examinations and functional assessments were performed. A radiographic assessment of the spine was performed.

Results: Out of 50 PsA patients (mean age of 45.50 ± 9.90 years), (males and females constituted 27 (54.0%) and 23 (46.0%) respectively), 76% had radiological axial involvement; (26%) with inflammatory axial pain and (50%) without inflammatory axial pain (subclinical). Three axial radiographic patterns were detected including spondylitis without sacroiliitis (15.78%), spondylitis with sacroiliitis (78.94%), and sacroiliitis without spondylitis (5.26%). In axial PsA patients, males were more affected than females (χ2=11.679, p = 0.003), with older age (H = 15.817, p < 0.001) and higher body mass index (BMI) (F = 5.145, p = 0.010), increased psoriasis duration (H = 9.826, p = 0.007) and severity (Η=25.171, p < 0.001), and more spinal movement limitations than PsA patients without axial involvement (F = 26.568, p < 0.001). Cervical involvement was higher than lumbar involvement. Axial radiographic severity assessed by the PsA Spondylitis Radiology Index was associated with increased disability as assessed by the Health assessment questionnaire (rs = 0.533, p = 0.001) and decreased quality of life assessed by short form-36 score (rs = -0.321, p = 0.050).

Conclusion: This study shows that a high percentage of PsA patients had axial involvement with a high percentage of them having asymptomatic radiological findings. The cervical spine is more frequently and severely affected than the lumbar spine. Axial PsA occurs in males more than females with characteristic older age and higher BMI, increased psoriasis duration, and more limitation of spinal mobility.

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来源期刊
CiteScore
2.30
自引率
0.00%
发文量
82
期刊介绍: Current Rheumatology Reviews publishes frontier reviews on all the latest advances on rheumatology and its related areas e.g. pharmacology, pathogenesis, epidemiology, clinical care, and therapy. The journal"s aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians in rheumatology.
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