Nuri Lee, Sora Cha, Jongman Kim, Yunmi Lee, Enjin Kang, Hyun Jung Kim, Seung Hui Hong, Jinsoo Rhu, Gyu-Seong Choi, Jae-Won Joh
{"title":"移植前呼吸机支持易导致死亡供肝移植后早期移植衰竭。","authors":"Nuri Lee, Sora Cha, Jongman Kim, Yunmi Lee, Enjin Kang, Hyun Jung Kim, Seung Hui Hong, Jinsoo Rhu, Gyu-Seong Choi, Jae-Won Joh","doi":"10.4174/astr.2023.105.3.141","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Deceased donor liver transplantation (DDLT) recipients in Korea are generally sicker due to an increasing organ shortage. In the present study, the risk factors for early 30-day liver graft failure after DDLT were identified.</p><p><strong>Methods: </strong>From August 2017 to February 2021, 265 adult DDLTs were performed. The characteristics of patients with and without 30-day graft failure were compared.</p><p><strong>Results: </strong>Liver graft failure occurred in 11 patients (17.7%) after DDLT. Baseline and perioperative characteristics of donors and recipients were not statistically significantly different between the 2 groups. The cumulative graft and overall survival rates at 6 months were 83.9% and 88.7%, respectively. Multivariate analysis showed ventilator support in the pretransplant period was a predisposing factor for 30-day graft failure after DDLT.</p><p><strong>Conclusion: </strong>Present study indicates that cautious decision is required when allocating DDLT in critically ill patients on mechanical ventilatory support.</p>","PeriodicalId":8071,"journal":{"name":"Annals of Surgical Treatment and Research","volume":null,"pages":null},"PeriodicalIF":1.2000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/86/63/astr-105-141.PMC10485352.pdf","citationCount":"0","resultStr":"{\"title\":\"Ventilator support in the pretransplant period predisposes early graft failure after deceased donor liver transplantation.\",\"authors\":\"Nuri Lee, Sora Cha, Jongman Kim, Yunmi Lee, Enjin Kang, Hyun Jung Kim, Seung Hui Hong, Jinsoo Rhu, Gyu-Seong Choi, Jae-Won Joh\",\"doi\":\"10.4174/astr.2023.105.3.141\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>Deceased donor liver transplantation (DDLT) recipients in Korea are generally sicker due to an increasing organ shortage. In the present study, the risk factors for early 30-day liver graft failure after DDLT were identified.</p><p><strong>Methods: </strong>From August 2017 to February 2021, 265 adult DDLTs were performed. The characteristics of patients with and without 30-day graft failure were compared.</p><p><strong>Results: </strong>Liver graft failure occurred in 11 patients (17.7%) after DDLT. Baseline and perioperative characteristics of donors and recipients were not statistically significantly different between the 2 groups. The cumulative graft and overall survival rates at 6 months were 83.9% and 88.7%, respectively. Multivariate analysis showed ventilator support in the pretransplant period was a predisposing factor for 30-day graft failure after DDLT.</p><p><strong>Conclusion: </strong>Present study indicates that cautious decision is required when allocating DDLT in critically ill patients on mechanical ventilatory support.</p>\",\"PeriodicalId\":8071,\"journal\":{\"name\":\"Annals of Surgical Treatment and Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2023-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/86/63/astr-105-141.PMC10485352.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of Surgical Treatment and Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.4174/astr.2023.105.3.141\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"SURGERY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Surgical Treatment and Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4174/astr.2023.105.3.141","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"SURGERY","Score":null,"Total":0}
Ventilator support in the pretransplant period predisposes early graft failure after deceased donor liver transplantation.
Purpose: Deceased donor liver transplantation (DDLT) recipients in Korea are generally sicker due to an increasing organ shortage. In the present study, the risk factors for early 30-day liver graft failure after DDLT were identified.
Methods: From August 2017 to February 2021, 265 adult DDLTs were performed. The characteristics of patients with and without 30-day graft failure were compared.
Results: Liver graft failure occurred in 11 patients (17.7%) after DDLT. Baseline and perioperative characteristics of donors and recipients were not statistically significantly different between the 2 groups. The cumulative graft and overall survival rates at 6 months were 83.9% and 88.7%, respectively. Multivariate analysis showed ventilator support in the pretransplant period was a predisposing factor for 30-day graft failure after DDLT.
Conclusion: Present study indicates that cautious decision is required when allocating DDLT in critically ill patients on mechanical ventilatory support.
期刊介绍：
Manuscripts to the Annals of Surgical Treatment and Research (Ann Surg Treat Res) should be written in English according to the instructions for authors. If the details are not described below, the style should follow the Uniform Requirements for Manuscripts Submitted to Biomedical Journals: Writing and Editing for Biomedical Publications available at International Committee of Medical Journal Editors (ICMJE) website (http://www.icmje.org).
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