尿荧光代谢组组成的可视化。为什么考虑初始尿浓度很重要?

IF 2.4 3区化学 Q3 CHEMISTRY, ANALYTICAL

Methods and Applications in Fluorescence Pub Date : 2023-07-19 DOI:10.1088/2050-6120/ace512

Katarína Dubayová, Anna Birková, Martin Lešo, Jaroslava Žilková, Anton Karabinoš, Mária Mareková, Marek Stupak

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引用次数: 0

摘要

尿液是一个高度复杂的荧光系统，其荧光受到许多因素的影响，包括在尿液综合荧光分析中经常被忽略的初始尿液浓度。在这项研究中，尿总荧光代谢组谱(uTFMP)被创建为一个三维荧光谱，通过几何级数稀释的尿液序列同步光谱。在重新计算初始尿浓度的3D数据后，使用为此目的设计的软件生成uTFMP。它可以以等高线图(俯视图)的形式呈现，也可以以更具说明性和直接的简单曲线的形式呈现，因此可用于各种医学应用。

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Visualization of the composition of the urinary fluorescent metabolome. Why is it important to consider initial urine concentration?

Urine is a highly complex fluorescent system, the fluorescence of which can be affected by many factors, including the often-ignored initial urine concentration in comprehensive fluorescent urine analysis. In this study, a total urine fluorescent metabolome profile (uTFMP) was created as a three-dimensional fluorescence profile of serial synchronous spectra of urine diluted by geometric progression. uTFMP was generated using software designed for this purpose after recalculating the 3D data concerning the initial urine concentration. It can be presented as a contour map (top view) or as a more illustrative and straightforward simple curve, thus usable in various medicinal applications.

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来源期刊

Methods and Applications in Fluorescence CHEMISTRY, ANALYTICALCHEMISTRY, PHYSICAL&n-CHEMISTRY, PHYSICAL

CiteScore

6.20

自引率

3.10%

发文量

期刊介绍： Methods and Applications in Fluorescence focuses on new developments in fluorescence spectroscopy, imaging, microscopy, fluorescent probes, labels and (nano)materials. It will feature both methods and advanced (bio)applications and accepts original research articles, reviews and technical notes.