治疗儿童不受控制的严重哮喘的生物药物。

IF 1.3 Q3 PEDIATRICS

Current Pediatric Reviews Pub Date : 2024-01-01 DOI:10.2174/1573396320666230912103115

Cristiana Indolfi, Angela Klain, Chiara Lucia Bencivenga, Elisabetta D'Addio, Giulio Dinardo, Alberto Decimo, Michele Miraglia Del Giudice

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引用次数: 0

摘要

近二十年前，用于治疗儿童严重过敏性哮喘的生物药物问世，对这一病症的临床过程和接受治疗的患者的生活质量都产生了重大影响。多年来，已开发出多种抑制哮喘发病机制分子靶点的分子。生物药物可显著改善重症哮喘患者的几项关键临床指标。在这篇综述中，我们简要总结了对患有严重哮喘的儿童和青少年进行生物治疗的证据。

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Biological Drugs for the Treatment of Uncontrolled Severe Asthma in Children.

The introduction of biological drugs for the treatment of severe allergic asthma in children, almost twenty years ago, had a substantial impact on both the pathology's clinical course and the quality of life of the patients who receive treatment. Over the years, several molecules have been developed that inhibit molecular targets involved in the pathogenesis of the asthmatic disease. Biological drugs demonstrate a significant improvement in several key clinical parameters in patients with severe asthma. In this review, we provide a concise summary of the evidence on biological therapy for children and adolescents with severe asthma.

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来源期刊

Current Pediatric Reviews PEDIATRICS-

CiteScore

4.30

自引率

0.00%

发文量

期刊介绍： Current Pediatric Reviews publishes frontier reviews on all the latest advances in pediatric medicine. The journal’s aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians in pediatric medicine.