用于再生医学和组织建模的心脏细胞片工程。

3区生物学 Q2 Biochemistry, Genetics and Molecular Biology

Progress in molecular biology and translational science Pub Date : 2023-01-01 Epub Date: 2023-06-17 DOI:10.1016/bs.pmbts.2023.03.003

Katsuhisa Matsuura, Tatsuya Shimizu

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引用次数: 0

摘要

干细胞生物学和组织工程是心脏组织构建的重要技术。我们已经成功地使用人iPS细胞衍生的心肌细胞和细胞片工程的大规模生产技术制造了人类心脏组织，我们正在开发再生医学和组织模型，将这种组织应用于心脏病研究。心脏组织的制造和收缩和电生理功能的组织功能评估技术是必不可少的，这导致了生物工程人类心脏组织功能的改善。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Cardiac cell sheet engineering for regenerative medicine and tissue modeling.

Stem cell biology and tissue engineering are essential techniques for cardiac tissue construction. We have succeeded in fabricating human cardiac tissue using the mass production technology of human iPS cell-derived cardiomyocytes and cell sheet engineering, and we are developing regenerative medicine and tissue models to apply this tissue to heart disease research. Cardiac tissue fabrication and tissue functional evaluation technologies for contractile and electrophysiological function are indispensable, which lead to the functional improvement of bioengineered human cardiac tissue.

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来源期刊

Progress in molecular biology and translational science 生物-生化与分子生物学

CiteScore

6.90

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Progress in Molecular Biology and Translational Science (PMBTS) provides in-depth reviews on topics of exceptional scientiﬁc importance. If today you read an Article or Letter in　Nature　or a Research Article or Report in　Science　reporting ﬁndings of exceptional importance, you likely will ﬁnd comprehensive coverage of that research area in a future　PMBTS　volume.