预测二尖瓣狭窄伴心房扑动的卒中和死亡率:一种机器学习方法

IF 1.1 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
Amer Rauf MBBS, Asif Ullah MBBS, Usha Rathi MBBS, Zainab Ashfaq MBBS, Hidayat Ullah MBBS, Amna Ashraf MBBS, Jateesh Kumar MBBS, Maria Faraz MS, Waheed Akhtar MBBS, Amin Mehmoodi MD, Jahanzeb Malik MBBS
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引用次数: 0

摘要

本研究假设智能梯度增强机(GBM)模型可以通过识别二尖瓣狭窄(MS)合并心房扑动(AFL)的合并症、心电图和超声心动图参数,预测脑血管事件和全因死亡率。方法利用机器学习模型作为统计分析工具,识别脑血管事件结局或死亡的关键危险因素和高危特征。结果共纳入2184例患者,包括他们的图表数据和影像学研究,GBM分析显示二尖瓣面积(MVA)、右心室收缩压、肺动脉压(PAP)、左心室射血分数(LVEF)、纽约心脏协会(NYHA)分级和手术是短暂性脑缺血发作(TIA/卒中)最重要的预测因素。MVA、PAP、LVEF、肌酐、血红蛋白和舒张压是全因死亡率的预测因子。结论GBM模型吸收了所有诊断方式的临床数据,显著提高了MS合并AFL预后的风险预测性能和关键变量的识别。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Predicting stroke and mortality in mitral stenosis with atrial flutter: A machine learning approach

Predicting stroke and mortality in mitral stenosis with atrial flutter: A machine learning approach

Background

Our study hypothesized that an intelligent gradient boosting machine (GBM) model can predict cerebrovascular events and all-cause mortality in mitral stenosis (MS) with atrial flutter (AFL) by recognizing comorbidities, electrocardiographic and echocardiographic parameters.

Methods

The machine learning model was used as a statistical analyzer in recognizing the key risk factors and high-risk features with either outcome of cerebrovascular events or mortality.

Results

A total of 2184 patients with their chart data and imaging studies were included and the GBM analysis demonstrated mitral valve area (MVA), right ventricular systolic pressure, pulmonary artery pressure (PAP), left ventricular ejection fraction (LVEF), New York Heart Association (NYHA) class, and surgery as the most significant predictors of transient ischemic attack (TIA/stroke). MVA, PAP, LVEF, creatinine, hemoglobin, and diastolic blood pressure were predictors for all-cause mortality.

Conclusion

The GBM model assimilates clinical data from all diagnostic modalities and significantly improves risk prediction performance and identification of key variables for the outcome of MS with AFL.

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来源期刊
CiteScore
3.40
自引率
0.00%
发文量
88
审稿时长
6-12 weeks
期刊介绍: The ANNALS OF NONINVASIVE ELECTROCARDIOLOGY (A.N.E) is an online only journal that incorporates ongoing advances in the clinical application and technology of traditional and new ECG-based techniques in the diagnosis and treatment of cardiac patients. ANE is the first journal in an evolving subspecialty that incorporates ongoing advances in the clinical application and technology of traditional and new ECG-based techniques in the diagnosis and treatment of cardiac patients. The publication includes topics related to 12-lead, exercise and high-resolution electrocardiography, arrhythmias, ischemia, repolarization phenomena, heart rate variability, circadian rhythms, bioengineering technology, signal-averaged ECGs, T-wave alternans and automatic external defibrillation. ANE publishes peer-reviewed articles of interest to clinicians and researchers in the field of noninvasive electrocardiology. Original research, clinical studies, state-of-the-art reviews, case reports, technical notes, and letters to the editors will be published to meet future demands in this field.
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