{"title":"一名患有杂合子凝血酶原G20210A突变的儿童成功进行肾脏再移植。","authors":"Ratna Acharya, Rachel Bush, Felicia Johns, Kiran Upadhyay","doi":"10.1177/15269248231189873","DOIUrl":null,"url":null,"abstract":"Prothrombin (PT) G20210Amutation is one risk factor for early renal allograft loss in pediatric kidney transplantation. There is no consensus whether screening for this mutation is necessary in all children undergoing transplantation. In asymptomatic children with this mutation, it is not clear whether prophylactic perioperative anticoagulation is beneficial. We describe a child with heterozygous PT G2021A mutation who underwent a successful re-transplantation following an early first kidney allograft loss. Parents of the patient provided consent for publication of this case report.","PeriodicalId":20671,"journal":{"name":"Progress in Transplantation","volume":"33 3","pages":"268-269"},"PeriodicalIF":0.6000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Successful Re-transplantation of Kidney in a Child with Heterozygous Prothrombin G20210A Mutation.\",\"authors\":\"Ratna Acharya, Rachel Bush, Felicia Johns, Kiran Upadhyay\",\"doi\":\"10.1177/15269248231189873\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Prothrombin (PT) G20210Amutation is one risk factor for early renal allograft loss in pediatric kidney transplantation. There is no consensus whether screening for this mutation is necessary in all children undergoing transplantation. In asymptomatic children with this mutation, it is not clear whether prophylactic perioperative anticoagulation is beneficial. We describe a child with heterozygous PT G2021A mutation who underwent a successful re-transplantation following an early first kidney allograft loss. Parents of the patient provided consent for publication of this case report.\",\"PeriodicalId\":20671,\"journal\":{\"name\":\"Progress in Transplantation\",\"volume\":\"33 3\",\"pages\":\"268-269\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2023-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Progress in Transplantation\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1177/15269248231189873\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/7/20 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"SURGERY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Progress in Transplantation","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/15269248231189873","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/7/20 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"SURGERY","Score":null,"Total":0}
Successful Re-transplantation of Kidney in a Child with Heterozygous Prothrombin G20210A Mutation.
Prothrombin (PT) G20210Amutation is one risk factor for early renal allograft loss in pediatric kidney transplantation. There is no consensus whether screening for this mutation is necessary in all children undergoing transplantation. In asymptomatic children with this mutation, it is not clear whether prophylactic perioperative anticoagulation is beneficial. We describe a child with heterozygous PT G2021A mutation who underwent a successful re-transplantation following an early first kidney allograft loss. Parents of the patient provided consent for publication of this case report.
期刊介绍:
Progress in Transplantation (PIT) is the official journal of NATCO, The Organization for Transplant Professionals. Journal Partners include: Australasian Transplant Coordinators Association and Society for Transplant Social Workers. PIT reflects the multi-disciplinary team approach to procurement and clinical aspects of organ and tissue transplantation by providing a professional forum for exchange of the continually changing body of knowledge in transplantation.