从西洋参果实中提取一种新的八酚型人参皂苷。

IF 1.9 3区化学 Q3 CHEMISTRY, APPLIED

Natural Product Research Pub Date : 2025-01-01 Epub Date: 2023-09-04 DOI:10.1080/14786419.2023.2252566

Yinping Jin, Zhengyi Qu, Shifeng Pang, Zheng Li, Yingping Wang, Hao Zhang

引用次数: 0

摘要

从西洋参果实中分离得到一种新的八酚型人参皂苷，命名为伪人参皂苷F12(1)，经鉴定其结构为6-O-[α- l- 2,3-环氧-鼠李糖吡喃-(1-2)-β- d -葡萄糖吡喃]- damar - 20s, 24r -环氧-3β， 6α，12β，25-四醇。此外，已知的生物碱β-羰基-1-羧酸(2)和anoectochine(3)均为首次从五加科植物中分离得到。新化合物1对乳腺癌细胞株MDA-MB-231的细胞毒性进行了评价。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A new ocotillol-type ginsenoside from American ginseng berry.

A new ocotillol-type ginsenoside, named pseudoginsenoside F₁₂ (1), was isolated from American ginseng berry, whose structure was elucidated as 6-O-[α-L-2,3-epoxy-rhamnopyranosyl-(1-2)-β-D-glucopyranosyl]-dammar-20S,24R-epoxy-3β, 6α,12β,25-tetraol. In addition, the known alkaloids β-carboline-1-carboxylic acid (2) and anoectochine (3) were isolated for the first time from the Araliaceae family. The new compound 1 was evaluated for cytotoxicity against MDA-MB-231 breast cancer cell line.

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来源期刊

Natural Product Research 化学-医药化学

CiteScore

5.10

自引率

9.10%

发文量

605

审稿时长

2.1 months

期刊介绍： The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds. The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal. Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section. All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.