父辈和母辈的问题饮酒及其成年子女的终生问题饮酒。

IF 1 4区 医学 Q4 GENETICS & HEREDITY
Twin Research and Human Genetics Pub Date : 2023-04-01 Epub Date: 2023-04-24 DOI:10.1017/thg.2023.12
Pyry N Sipilä, Anna Keski-Rahkonen, Joni V Lindbohm, Richard J Rose, Jaakko Kaprio
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引用次数: 0

摘要

父母酗酒与其青少年后代酗酒有关,但这种关联是否会延伸到后代的成年期?我们在一个基于人口的芬兰双胞胎家庭队列(FinnTwin16)中,研究了父亲和母亲的问题饮酒与其成年后代终生问题饮酒的关系。在子女 16 岁时,母亲和父亲分别对问题性饮酒(经马尔默修正的密歇根酒精中毒筛查测试)进行了自我报告。孩子们在二十多岁(21-28 岁)和三十多岁(31-37 岁)时报告了同一测试的终生扩展版。有完整数据的二十多岁的儿子有 1235 人,女儿有 1461 人;三十多岁的儿子有 991 人,女儿有 1278 人。父亲与其成年子女的问题性饮酒之间的相关性从 0.12 到 0.18 不等。母亲与其成年子女之间的相关系数为 0.09 至 0.14。在多变量模型中,对潜在混杂因素的调整对观察到的相关性几乎没有影响。在本研究中,父母的问题性饮酒与其成年子女的终生问题性饮酒略有关联。即使子女已经年过四旬,也能发现这种关联。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Paternal and Maternal Problem Drinking and Lifetime Problem Drinking of Their Adult Children.

Parents' alcohol use is associated with alcohol use of their adolescent offspring, but does this association extend to the adulthood of the offspring? We examined associations of paternal and maternal problem drinking with lifetime problem drinking of their adult offspring prospectively assessed in a population-based Finnish twin-family cohort (FinnTwin16). Problem drinking (Malmö-modified Michigan Alcoholism Screening Test) was self-reported separately by mothers and fathers when their children were 16. The children reported on an extended lifetime version of the same measure during their mid-twenties (21-28 years) and mid-thirties (31-37 years). 1235 sons and 1461 daughters in mid-twenties and 991 sons and 1278 daughters in mid-thirties had complete data. Correlations between fathers' and their adult children's problem drinking ranged from .12 to .18. For mothers and their adult children, these correlations ranged from .09 to .14. In multivariate models, adjustment for potential confounders had little effect on the observed associations. In this study, parental problem drinking was modestly associated with lifetime problem drinking of their adult children. This association could be detected even when the children had reached the fourth decade of life.

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来源期刊
Twin Research and Human Genetics
Twin Research and Human Genetics 医学-妇产科学
CiteScore
1.50
自引率
11.10%
发文量
37
审稿时长
6-12 weeks
期刊介绍: Twin Research and Human Genetics is the official journal of the International Society for Twin Studies. Twin Research and Human Genetics covers all areas of human genetics with an emphasis on twin studies, genetic epidemiology, psychiatric and behavioral genetics, and research on multiple births in the fields of epidemiology, genetics, endocrinology, fetal pathology, obstetrics and pediatrics. Through Twin Research and Human Genetics the society aims to publish the latest research developments in twin studies throughout the world.
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