18F-FDG PET/CT在单克隆浆细胞疾病中的应用。

IF 0.9 4区医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Hellenic journal of nuclear medicine Pub Date : 2023-05-01

Anna Paschali

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引用次数: 0

摘要

浆细胞疾病是由骨髓中淋巴浆细胞的单克隆增殖引起的一组异质性疾病。多发性骨髓瘤（MM）是最严重和最普遍的浆细胞异常，中位发病年龄为60岁。MM表现出显著的遗传、生物学和临床异质性，随后的成像异质性在当代成像模式（PET/CT和MRI）中很明显。有证据表明，MM之前总是有意义不明的单克隆gammopathy（MGUS）和闷烧性多发性骨髓瘤的前体阶段。

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¹⁸F-FDG PET/CT in monoclonal plasma cell disorders.

Plasma cell disorders are a heterogeneous group caused by the monoclonal proliferation of lymphoplasmacytic cells in the bone marrow. Multiple Myeloma (MM) is the most serious and prevalent plasma cell dyscrasia, with a median age of onset of 60 years.MM displays significant genetic, biological and clinical heterogeneity with subsequent imaging heterogeneity, evident in contemporary imaging modalities (PET/CT and MRI). Evidence suggests that MM is always preceded by precursor stages of monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma.

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来源期刊

Hellenic journal of nuclear medicine 医学-核医学

CiteScore

1.40

自引率

6.70%

发文量

审稿时长

>12 weeks

期刊介绍： The Hellenic Journal of Nuclear Medicine published by the Hellenic Society of Nuclear Medicine in Thessaloniki, aims to contribute to research, to education and cover the scientific and professional interests of physicians, in the field of nuclear medicine and in medicine in general. The journal may publish papers of nuclear medicine and also papers that refer to related subjects as dosimetry, computer science, targeting of gene expression, radioimmunoassay, radiation protection, biology, cell trafficking, related historical brief reviews and other related subjects. Original papers are preferred. The journal may after special agreement publish supplements covering important subjects, dully reviewed and subscripted separately.