William J. Scheuing , Anthony M. Reginato , Mery Deeb , Sevtap Acer Kasman
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引用次数: 0
摘要
本综述旨在概述骨关节炎(OA)作为全球最常见关节疾病之一的现状。尽管骨关节炎是全球第11位致残原因,但其患病率、年发病率和残疾生活年数都在增加,尤其是在发达国家和发展中国家。侵蚀性手部 OA 约占总人口的 10%,与非侵蚀性手部 OA 相比,侵蚀性手部 OA 的临床负担更高。膝关节和髋关节 OA(而非手部 OA)患者罹患心血管疾病和全因死亡率的风险也会增加。此外,在大多数国家,OA 对医疗成本的影响也很大。由于获得医疗和手术治疗的机会有限,最近流行的 COVID-19 进一步加重了 OA 患者的疾病负担。随着预期寿命的延长和全球人口的老龄化,预计 OA 的负担将进一步加重。因此,本综述强调了提高人口和政策制定者对肥胖和损伤等风险因素的认识以及对 OA 进行早期干预和管理以控制未来疾病负担的重要性。
The burden of osteoarthritis: Is it a rising problem?
The objective of this review is to provide an overview of the current status of osteoarthritis (OA) as one of the most common joint disorders worldwide. Despite being the 11th cause of disability globally, there has been an increase in the prevalence, annual incidence, and years lived with disability of OA, particularly in developed and developing countries. Erosive hand OA, which affects approximately 10% of the general population, has been associated with a higher clinical burden compared to non-erosive hand OA. Patients with knee and hip OA, but not hand OA, are also at an increased risk of cardiovascular disease and all-cause mortality. Furthermore, OA has a significant contribution to healthcare costs in most countries. The recent COVID-19 pandemic has further exacerbated the disease burden of OA patients due to limited access to medical and surgical treatment. With increasing life expectancy and the aging of the global population, the burden of OA is expected to worsen. Therefore, this review highlights the importance of improving population and policymaker awareness of risk factors, such as obesity and injury, as well as early intervention and management of OA to control the future burden of the disease.
期刊介绍:
Evidence-based updates of best clinical practice across the spectrum of musculoskeletal conditions.
Best Practice & Research: Clinical Rheumatology keeps the clinician or trainee informed of the latest developments and current recommended practice in the rapidly advancing fields of musculoskeletal conditions and science.
The series provides a continuous update of current clinical practice. It is a topical serial publication that covers the spectrum of musculoskeletal conditions in a 4-year cycle. Each topic-based issue contains around 200 pages of practical, evidence-based review articles, which integrate the results from the latest original research with current clinical practice and thinking to provide a continuous update.
Each issue follows a problem-orientated approach that focuses on the key questions to be addressed, clearly defining what is known and not known. The review articles seek to address the clinical issues of diagnosis, treatment and patient management. Management is described in practical terms so that it can be applied to the individual patient. The serial is aimed at the physician in both practice and training.