严重哮喘的示波测量:技术现状和未来展望。

IF 2.9 3区 医学 Q2 RESPIRATORY SYSTEM
Expert Review of Respiratory Medicine Pub Date : 2023-07-01 Epub Date: 2023-07-20 DOI:10.1080/17476348.2023.2237872
Francesco Menzella, Leonardo Antonicelli, Marcello Cottini, Gianluca Imeri, Lorenzo Corsi, Fabiano Di Marco
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引用次数: 0

摘要

引言:大约3-10%的哮喘患者患有严重哮喘(SA)。SA患者在日常生活中的损伤更大,费用也高得多。即使哮喘影响整个支气管树,小气道也被认为是气流受限的主要部位。有几种研究小气道功能障碍(SAD)的工具,但最有趣的肯定是示波法。尽管进行了几项研究,但示波法在哮喘中的临床实用性仍然存在疑问。本文旨在为在临床实践中使用示波法改善SA的管理提供证据。涵盖的领域:在ATLANTIS的研究中,SAD在所有严重程度上都非常明显。有各种工具可用于评估SAD,当然,综合使用这些工具可以提供完整和详细的信息。然而,最合适的方法是示波法,通过使用小压力脉冲或小压力正弦波来实现临床常规。专家意见:尽管示波器的技术实现方式不同,但它是确定SAD对哮喘及其控制影响的最佳工具。示波法在选择合适的药物方面也将越来越有用,在临床实践中有更广泛的推广空间。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Oscillometry in severe asthma: the state of the art and future perspectives.

Introduction: Approximately 3-10% of people with asthma have severe asthma (SA). Patients with SA have greater impairment in daily life and much higher costs. Even if asthma affects the entire bronchial tree, small airways have been recognized as the major site of airflow limitation. There are several tools for studying small airway dysfunction (SAD), but certainly the most interesting is oscillometry. Despite several studies, the clinical usefulness of oscillometry in asthma is still in question. This paper aims to provide evidence supporting the use of oscillometry to improve the management of SA in clinical practice.

Areas covered: In the ATLANTIS study, SAD was strongly evident across all severity. Various tools are available for evaluation of SAD, and certainly an integrated use of these can provide complete and detailed information. However, the most suitable method is oscillometry, implemented for clinical routine by using either small pressure impulses or small pressure sinusoidal waves.

Expert opinion: Oscillometry, despite its different technological implementations is the best tool for determining the impact of SAD on asthma and its control. Oscillometry will also be increasingly useful for choosing the appropriate drug, and there is ample room for a more widespread diffusion in clinical practice.

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来源期刊
CiteScore
6.80
自引率
2.60%
发文量
90
期刊介绍: Coverage will include the following key areas: - Prospects for new and emerging therapeutics - Epidemiology of disease - Preventive strategies - All aspects of COPD, from patient self-management to systemic effects of the disease and comorbidities - Improved diagnostic methods, including imaging techniques, biomarkers and physiological tests. - Advances in the treatment of respiratory infections and drug resistance issues - Occupational and environmental factors - Progress in smoking intervention and cessation methods - Disease and treatment issues for defined populations, such as children and the elderly - Respiratory intensive and critical care - Updates on the status and advances of specific disease areas, including asthma, HIV/AIDS-related disease, cystic fibrosis, COPD and sleep-disordered breathing morbidity
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