放射性药物68Ga-PSMA-11在捷克两个工厂的制备比较。

Q3 Pharmacology, Toxicology and Pharmaceutics

Ceska a Slovenska Farmacie Pub Date : 2023-01-01

Michal Budinský, Vendula Janků

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引用次数: 0

摘要

放射性药物68Ga-PSMA-11是捷克共和国核医学部门最新的正电子放射性药物之一。所述放射性药物制备可使用用于合成的模块手工或仪器进行。尽管制备的技术难度较大，但两种方法合成该放射性药物的成功率都非常高，并且所评价的放射性药物的质量参数与手工和仪器制备方法相当。此外，在职业暴露方面，68Ga-PSMA-11的制备对全身和手指剂量测定结果没有显著影响。

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Comparison of the preparation of the radiopharmaceutical 68Ga-PSMA-11 at two Czech worksites.

Radiopharmaceutical 68Ga-PSMA-11 is one of the newest positron radiopharmaceuticals available for nuclear medicine departments in the Czech Republic. The radiopharmaceutical preparation can be carried out manually or instrumentally using modules for synthesis. Despite the greater technological difficulty of preparation, the success of synthesis of this radiopharmaceutical by both methods is very high, and the evaluated quality parameters of the radiopharmaceutical are comparable by both manual and instrumental preparation methods. Also, regarding professional exposure, the preparation of 68Ga-PSMA-11 does not significantly affect the whole-body and finger dosimetry results.

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来源期刊

Ceska a Slovenska Farmacie Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science

CiteScore

0.90

自引率

0.00%

发文量

期刊介绍： Přehledový článek je zaměřen zejména na metody přípravy, charakterizaci mikročástic a dále na charakteristiku a příklady jejich možného využití ve farmakoterapii. Mikročástice jako...