Qiu Lin Ge, Xiao Ming Teng, Miao Xin Chen, Kun Ming Li, Ernest Hung Yu Ng, Zhi Qin Chen
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引用次数: 0
摘要
目的：根据Bologna标准，评估胚胎库对卵巢反应不良（POR）的累积活产率（CLBR）和活产时间（TTLB）的影响。方法：本回顾性研究共纳入276例接受POR体外受精的不孕妇女。他们被分为两组，其中（n = 121）或不带（n = 155）主治医师自行决定的胚胎库。在24小时内，两组分别开始了656个和405个刺激周期 结果：两组的生化妊娠、临床妊娠、持续妊娠和每次分娩的活产率具有可比性（p > 银行组的CLBR显著低于非银行组（31.4%（38/121）和43.2%（67/151），p p p 结论：与没有胚胎库相比，根据Bologna标准接受POR体外受精的女性的胚胎库减少了CLBR并延长了TTLB。
The impact of the embryo banking on the cumulative live birth rate in women with poor ovarian response according to the Bologna criteria.
Purpose: To evaluate the impact of embryo banking on the cumulative live birth rate (CLBR) and the time to live birth (TTLB) in poor ovarian responders (POR) according to the Bologna criteria.
Methods: A total of 276 infertile women undergoing IVF with POR were included in this retrospective study. They were divided into two groups with (n = 121) or without (n = 155) embryo banking at the discretion of the attending physicians. A total of 656 and 405 stimulation cycles were started in the two groups respectively during the 24 month follow-up.
Results: The biochemical pregnancy, clinical pregnancy, ongoing pregnancy, and live birth rate per transfer were comparable between two groups (p > 0.05). The CLBR was significantly lower in the banking group than in the non-banking group (31.4% (38/121) and 43.2% (67/151), p < 0.05). TTLB was significantly longer in the banking group (20.5 months vs. 16.0 months, p < 0.001). In the Kaplan-Meier analysis, the cumulative incidence of live birth was significantly lower in the banking group compared with the non-banking group (Log rank test, chi-square = 21.958, p < 0.001).
Conclusions: Embryo banking in women undergoing IVF with POR based on the Bologna criteria reduces CLBR and lengthens TTLB when compared with no embryo banking.
期刊介绍：
Reproductive Medicine and Biology (RMB) is the official English journal of the Japan Society for Reproductive Medicine, the Japan Society of Fertilization and Implantation, the Japan Society of Andrology, and publishes original research articles that report new findings or concepts in all aspects of reproductive phenomena in all kinds of mammals. Papers in any of the following fields will be considered: andrology, endocrinology, oncology, immunology, genetics, function of gonads and genital tracts, erectile dysfunction, gametogenesis, function of accessory sex organs, fertilization, embryogenesis, embryo manipulation, pregnancy, implantation, ontogenesis, infectious disease, contraception, etc.
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