欧洲医护人员接种疫苗前感染SARS-CoV-2的相关因素

IF 2.4 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Ihab Mansour, Alessandro Godono, Emanuele Sansone, Giovanni Visci, Gianluca Spiteri, Maria Grazia Lourdes Monaco, Dana Mates, Agripina Rascu, Xavier Duval, Enrico Pira, Catalina Ciocan, Francesco Violante, Vittorio Lodi, Giuseppe De Palma, Emma Sala, Marco Dell'Olmo, Corrado Negro, Loretta Casolari, Masha Abedini, Giorgia Ditano, Shuffield Asafo, Paolo Boffetta, Orchestra Wp Working Group
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引用次数: 1

摘要

背景:卫生保健工作者(HCWs)处于当前大流行的第一线。我们的目的是确定SARS-CoV-2感染的决定因素以及卫生保健工作者在接种疫苗前佩戴的个人防护装备(PPE)的有效性。方法:根据欧洲10个中心公立医院和公共卫生部门的38,793名卫生工作者的PCR阳性结果和社会人口学特征提取SARS-CoV-2感染数据。我们拟合了特定队列的多变量逻辑回归模型,以确定感染的决定因素,并使用随机效应荟萃分析将结果结合起来。结果:卫生保健员接种疫苗前总体感染率为9.58%。感染与出现特定症状有关;未发现社会人口因素与感染风险增加之间存在关联。在第一波和第二波COVID大流行期间,使用个人防护装备,特别是FFP2/FFP3口罩具有不同的保护作用。结论:使用口罩是卫生工作者预防SARS-CoV-2感染最有效的PPE。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Factors Associated with SARS-CoV-2 Infection before Vaccination among European Health Care Workers.

Background: Health care workers (HCWs) were on the frontline of the current pandemic. We aimed at identifying determinants of SARS-CoV-2 infection and the effectiveness of personal protection equipment (PPE) worn by HCWs before vaccination.

Methods: We abstracted data on SARS-CoV-2 infection based on positive PCR results and sociodemographic characteristics of 38,793 HCWs from public hospitals and public health authorities from 10 European centers. We fitted cohort-specific multivariate logistic regression models to identify determinants of infection and combined the results using random-effects meta-analyses.

Results: The overall prevalence of infection before vaccination among HCWs was 9.58%. Infection was associated with the presence of selected symptoms; no association was found between sociodemographic factors and increased risk of infection. The use of PPE and particularly FFP2/FFP3 masks had a different protective effect during the first and second waves of the COVID pandemic.

Conclusions: The study provides evidence that mask use was the most effective PPE in preventing SARS-CoV-2 infection among HCWs.

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来源期刊
Medicina Del Lavoro
Medicina Del Lavoro 医学-公共卫生、环境卫生与职业卫生
CiteScore
4.70
自引率
7.40%
发文量
42
审稿时长
>12 weeks
期刊介绍: La Medicina del Lavoro is a bimonthly magazine founded in 1901 by L. Devoto, and then directed by L. Prieti, E. Vigliani, V. Foà, P.A. Bertazzi (Milan). Now directed by A. Mutti (Parma), the magazine is the official Journal of the Italian Society of Occupational Medicine (SIML), aimed at training and updating all professionals involved in prevention and cure of occupational diseases.
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