Rathod Aishwarya, Jaiswal Priyanka, Bajaj Pavan, Kale Bhairavi, Masurkar Deepika
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Periodontal pocket depth (PPD), R-CAL, papillary bleeding index (PBI), and PI were the secondary outcome. Clinical and radiographic measurements were recorded at baseline and 6 months postoperatively.</p><p><strong>Results: </strong>No significant difference was observed between the two groups in terms of PPD reduction (4.64 ± 0.74 mm vs 4.07 ± 0.99 mm), clinical attachment loss (CAL) gain (4.64 ± 0.74 mm vs 3.92 ± 0.99 mm) and radiographic defect depth reduction (2.41 ± 0.32 mm vs 2.40 ± 0.27 mm) for test and control groups, respectively.</p><p><strong>Conclusion: </strong>At 6-month post-surgery, both treatment modalities demonstrated statistically significant improvements with regard to CAL gains, PPD reduction, and reduction in radiographic defect depth.</p><p><strong>Clinical relevance: </strong>The NcHA and HA + β-TCP with A-PRF is a novel material used in the treatment of infrabony defect for periodontal regeneration. 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引用次数: 0
摘要
目的:评估并比较纳米结晶羟基磷灰石(NcHA)与高级富血小板纤维蛋白(A-PRF)以及羟基磷灰石强化β磷酸三钙(HA + β-TCP)与A-PRF在临床和影像学上使用锥束计算机断层扫描(CBCT)治疗人体骨下缺损的效果:试验组和对照组共有 28 个缺损,其中试验组和对照组分别有 14 个缺损。共有 28 名患者参与研究。试验组(A 组)使用 NHA 和 A-PRF 治疗,对照组(B 组)使用 HA + β-TCP 和 A-PRF 治疗。骨缺损填充是调查的主要结果。牙周袋深度(PPD)、R-CAL、乳头出血指数(PBI)和 PI 是次要结果。在基线和术后 6 个月记录临床和放射学测量结果:结果:试验组和对照组在 PPD 减少量(4.64 ± 0.74 mm vs 4.07 ± 0.99 mm)、临床附着丧失(CAL)增加量(4.64 ± 0.74 mm vs 3.92 ± 0.99 mm)和放射学缺损深度减少量(2.41 ± 0.32 mm vs 2.40 ± 0.27 mm)方面无明显差异:结论:术后6个月时,两种治疗方式在CAL增加、PPD减少和放射学缺损深度减少方面都有统计学意义上的显著改善:NcHA和HA+β-TCP与A-PRF是一种新型材料,可用于治疗牙周缺损,促进牙周再生。NcHA和HA+β-TCP与A-PRF需要考虑用于骨缺损填充的生物材料。
Evaluating and Comparing the Effectiveness of Nano-HA and HA + β-TCP with A-PRF Clinically and Radiographically in the Treatment of Human Infrabony Defects.
Aim: To evaluate and compare the effectiveness of nanocrystalline hydroxyapatite (NcHA) with advanced platelet-rich fibrin (A-PRF) and hydroxyapatite-reinforced beta tricalcium phosphate (HA + β-TCP) with A-PRF in the treatment of human infrabony defects clinically and radiographically using cone-beam computed tomography (CBCT).
Materials and methods: There were a total of 28 defects, with 14 defects in the test and control groups, respectively. There were total 28 patients were involved in the study. The test group (group A) was treated with NHA and A-PRF, while the control group (group B) was treated with HA + β-TCP and A-PRF. Bone defect fill was the primary result of the investigation. Periodontal pocket depth (PPD), R-CAL, papillary bleeding index (PBI), and PI were the secondary outcome. Clinical and radiographic measurements were recorded at baseline and 6 months postoperatively.
Results: No significant difference was observed between the two groups in terms of PPD reduction (4.64 ± 0.74 mm vs 4.07 ± 0.99 mm), clinical attachment loss (CAL) gain (4.64 ± 0.74 mm vs 3.92 ± 0.99 mm) and radiographic defect depth reduction (2.41 ± 0.32 mm vs 2.40 ± 0.27 mm) for test and control groups, respectively.
Conclusion: At 6-month post-surgery, both treatment modalities demonstrated statistically significant improvements with regard to CAL gains, PPD reduction, and reduction in radiographic defect depth.
Clinical relevance: The NcHA and HA + β-TCP with A-PRF is a novel material used in the treatment of infrabony defect for periodontal regeneration. The NcHA and HA + β-TCP with A-PRF need to consider biomaterials for bone defect fill.
期刊介绍:
The Journal of Contemporary Dental Practice (JCDP), is a peer-reviewed, open access MEDLINE indexed journal. The journal’s full text is available online at http://www.thejcdp.com. The journal allows free access (open access) to its contents. Articles with clinical relevance will be given preference for publication. The Journal publishes original research papers, review articles, rare and novel case reports, and clinical techniques. Manuscripts are invited from all specialties of dentistry i.e., conservative dentistry and endodontics, dentofacial orthopedics and orthodontics, oral medicine and radiology, oral pathology, oral surgery, orodental diseases, pediatric dentistry, implantology, periodontics, clinical aspects of public health dentistry, and prosthodontics.