健康伙伴:调查已婚和同居夫妇的社会遗传效应。

IF 2.6 4区 医学 Q2 BEHAVIORAL SCIENCES
Behavior Genetics Pub Date : 2023-07-01 Epub Date: 2023-06-07 DOI:10.1007/s10519-023-10147-w
Kasper Otten, Jornt J Mandemakers
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引用次数: 0

摘要

伴侣在饮酒、吸烟、体育锻炼和肥胖等健康行为和结果方面彼此相似。虽然这与暗示伴侣影响的社会传染理论是一致的,但由于同类交配和环境混杂,要确定因果关系是非常困难的。我们将已婚/同居夫妇双方的基因数据与他们的健康行为和结果的纵向数据相结合,为研究长期伴侣关系中的健康社会传染提供了一种新方法。我们研究了已婚/同居夫妇中伴侣的遗传倾向对三种健康结果和行为(体重指数、吸烟和饮酒)的影响。我们使用了健康与退休研究(Health and Retirement Study)和英国老龄化纵向研究(English Longitudinal Study of Ageing)的纵向数据,这些数据包含了夫妻双方的健康结果和基因型。结果显示,随着时间的推移,BMI、吸烟和饮酒的变化取决于伴侣对这些特征的遗传倾向。这些发现强调了人们所处的社会环境对其健康的重要性,并突出了针对夫妻健康干预的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Partners in Health: Investigating Social Genetic Effects Among Married and Cohabiting Couples.

Partners in Health: Investigating Social Genetic Effects Among Married and Cohabiting Couples.

Partners in Health: Investigating Social Genetic Effects Among Married and Cohabiting Couples.

Partners in Health: Investigating Social Genetic Effects Among Married and Cohabiting Couples.

Partners resemble each other in health behaviors and outcomes such as alcohol use, smoking, physical activity, and obesity. While this is consistent with social contagion theory suggesting partner influence, it is notoriously difficult to establish causality because of assortative mating and contextual confounding. We offer a novel approach to studying social contagion in health in long-term partnerships by combining genetic data of both partners in married/cohabiting couples with longitudinal data on their health behaviors and outcomes. We examine the influence of the partner's genetic predisposition for three health outcomes and behaviors (BMI, smoking, and drinking) among married/cohabiting couples. We use longitudinal data from the Health and Retirement Study and the English Longitudinal Study of Ageing with data on health outcomes and genotypes for both partners. Results show that changes over time in BMI, smoking, and drinking depend on the partner's genetic predispositions to these traits. These findings underline the importance of people's social surroundings for their health and highlight the potential of targeting health interventions at couples.

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来源期刊
Behavior Genetics
Behavior Genetics 生物-行为科学
CiteScore
4.90
自引率
7.70%
发文量
30
审稿时长
6-12 weeks
期刊介绍: Behavior Genetics - the leading journal concerned with the genetic analysis of complex traits - is published in cooperation with the Behavior Genetics Association. This timely journal disseminates the most current original research on the inheritance and evolution of behavioral characteristics in man and other species. Contributions from eminent international researchers focus on both the application of various genetic perspectives to the study of behavioral characteristics and the influence of behavioral differences on the genetic structure of populations.
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