The contemporary immunoassays for HIV diagnosis: a concise overview.

IF 0.4 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

Asian Biomedicine Pub Date : 2023-02-01 DOI:10.2478/abm-2023-0038

Abdullah, Misbahud Din, Abdul Waris, Muddasir Khan, Sajjad Ali, Riaz Muhammad, Muhammad Salman

引用次数: 0

Abstract

Abstract Recent advances in human immunodeficiency virus (HIV) diagnostics have improved the management of disease progression significantly, which have also boosted the efficacy of antiviral therapies. The detection of HIV at the earliest is very important. A highly recognized and effective virological biomarker for acute HIV infections is p24 antigen. This brief overview is based on advances of HIV diagnosis while focusing on the latest HIV testing technologies including HIV-specific antigens detecting assays of both anti-HIV antibodies and p24 antigen. In addition to other emerging molecular diagnostics for acute HIV infection, the utilization of p24 antigen has been summarized. Moreover, it has been explained how these immunoassays have reduced the window period for detection of HIV in the acute stage of infection.

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当代艾滋病毒诊断的免疫测定:简明概述。

人类免疫缺陷病毒(HIV)诊断的最新进展显著改善了疾病进展的管理，这也提高了抗病毒治疗的疗效。尽早发现HIV是非常重要的。p24抗原是一种高度认可和有效的急性HIV感染病毒学生物标志物。本文简要概述了艾滋病诊断的进展，同时重点介绍了最新的艾滋病检测技术，包括抗艾滋病抗体和p24抗原的艾滋病特异性抗原检测测定。除了其他新兴的分子诊断急性HIV感染，p24抗原的利用已被总结。此外，它已经解释了这些免疫测定如何减少了在感染的急性阶段检测艾滋病毒的窗口期。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Asian Biomedicine 医学-医学：研究与实验

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Asian Biomedicine: Research, Reviews and News (ISSN 1905-7415 print; 1875-855X online) is published in one volume (of 6 bimonthly issues) a year since 2007. [...]Asian Biomedicine is an international, general medical and biomedical journal that aims to publish original peer-reviewed contributions dealing with various topics in the biomedical and health sciences from basic experimental to clinical aspects. The work and authorship must be strongly affiliated with a country in Asia, or with specific importance and relevance to the Asian region. The Journal will publish reviews, original experimental studies, observational studies, technical and clinical (case) reports, practice guidelines, historical perspectives of Asian biomedicine, clinicopathological conferences, and commentaries Asian biomedicine is intended for a broad and international audience, primarily those in the health professions including researchers, physician practitioners, basic medical scientists, dentists, educators, administrators, those in the assistive professions, such as nurses, and the many types of allied health professionals in research and health care delivery systems including those in training.