Review of the Etiology, Diagnosis, and Management of Left Ventricular Thrombus.

IF 2 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Cardiology in Review Pub Date : 2025-01-01 Epub Date: 2023-06-16 DOI:10.1097/CRD.0000000000000572
Jared M Feldman, William H Frishman, Wilbert S Aronow
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引用次数: 0

Abstract

The incidence of left ventricular (LV) thrombus following acute myocardial infarction has declined significantly due to recent advancements in reperfusion and antithrombotic therapies. The development of LV thrombus depends on Virchow's triad: endothelial injury following myocardial infarction, blood stasis from LV dysfunction, and hypercoagulability. Diagnostic modalities for LV thrombus include transthoracic echocardiography and late gadolinium enhancement cardiac magnetic resonance imaging. Anticoagulation with direct oral anticoagulants or vitamin K antagonists for 3 months following initial diagnosis of LV thrombus remains the treatment of choice for LV thrombus. However, further evidence is needed to demonstrate the noninferiority of direct oral anticoagulants compared with vitamin K antagonists for the prevention of thromboembolic events.

左心室血栓的病因、诊断和治疗综述。
由于最近再灌注和抗血栓治疗的进展,急性心肌梗死后左心室血栓的发生率显著下降。左室血栓的形成取决于Virchow的三要素:心肌梗死后的内皮损伤、左室功能障碍引起的血瘀和高凝性。左室血栓的诊断方法包括经胸超声心动图和晚期钆增强心脏磁共振成像。在最初诊断为左室血栓后,直接口服抗凝剂或维生素K拮抗剂抗凝3个月仍然是左室血栓的首选治疗方法。然而,需要进一步的证据来证明直接口服抗凝剂与维生素K拮抗剂在预防血栓栓塞事件方面的非劣效性。
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来源期刊
Cardiology in Review
Cardiology in Review CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
4.60
自引率
0.00%
发文量
76
审稿时长
>12 weeks
期刊介绍: The mission of Cardiology in Review is to publish reviews on topics of current interest in cardiology that will foster increased understanding of the pathogenesis, diagnosis, clinical course, prevention, and treatment of cardiovascular disorders. Articles of the highest quality are written by authorities in the field and published promptly in a readable format with visual appeal
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