Low medication adherence and its associated factors among patients with type 2 diabetes mellitus attending Amana Hospital in Dar es Salaam, Tanzania: a cross-sectional study.

IF 2.3 4区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

International Health Pub Date : 2024-03-04 DOI:10.1093/inthealth/ihad042

Irene F Doya, James J Yahaya, Advera I Ngaiza, Deogratius Bintabara

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引用次数: 0

Abstract

Background: Low medication adherence among patients with type 2 diabetes mellitus (T2DM) is associated with significant morbidity and mortality globally. We investigated the prevalence of low medication adherence and its associated factors among patients with T2DM.

Methods: We used the Bengali version of the 8-item Morisky Medication Adherence Scale (MMAS-8) in measuring medication adherence among patients with T2DM who were attending the diabetes clinic at Amana Regional Referral Hospital in Dar es Salaam, Tanzania, from December 2021 to May 2022. Binary logistic regression analysis under multivariate analysis was used to determine the predictors of low medication adherence after controlling for confounders. A two-tailed p-value <0.05 was considered significant.

Results: The prevalence of low medication adherence was 36.7% (91/248) of the subjects included in the study. Lack of formal education (adjusted odds ratio [AOR] 5.3 [95% confidence interval {CI} 1.717 to 16.312], p=0.004), having comorbidities (AOR 2.1 [95% CI 1.134 to 3.949], p=0.019) and drinking alcohol (AOR 3.5 [95% CI 1.603 to 7.650], p=0.031) were the independent predictors of low medication adherence.

Conclusion: More than one-third of the patients with T2DM in this study had low medication adherence. Our study also showed that a lack of formal education, having comorbidities and drinking alcohol were significantly associated with low medication adherence.

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坦桑尼亚达累斯萨拉姆阿玛纳医院 2 型糖尿病患者服药依从性低及其相关因素：一项横断面研究。

背景：在全球范围内，2型糖尿病（T2DM）患者用药依从性低与严重的发病率和死亡率有关。我们调查了 T2DM 患者用药依从性低的发生率及其相关因素：我们使用孟加拉语版的 8 项莫里斯基用药依从性量表（MMAS-8）来测量 2021 年 12 月至 2022 年 5 月期间在坦桑尼亚达累斯萨拉姆的阿玛纳地区转诊医院糖尿病门诊就诊的 T2DM 患者的用药依从性。在控制了混杂因素后，采用多变量分析下的二元逻辑回归分析来确定用药依从性低的预测因素。双尾 p 值结果：在研究对象中，用药依从性低的比例为 36.7%（91/248）。缺乏正规教育（调整后比值比 [AOR] 5.3 [95% 置信区间 {CI} 1.717 至 16.312]，p=0.004）、合并症（AOR 2.1 [95% CI 1.134 至 3.949]，p=0.019）和饮酒（AOR 3.5 [95% CI 1.603 至 7.650]，p=0.031）是药物依从性低的独立预测因素：本研究中超过三分之一的 T2DM 患者服药依从性较低。结论：本研究中超过三分之一的 T2DM 患者服药依从性较低，我们的研究还表明，缺乏正规教育、患有合并症和饮酒与服药依从性较低有显著关联。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

4.50

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： International Health is an official journal of the Royal Society of Tropical Medicine and Hygiene. It publishes original, peer-reviewed articles and reviews on all aspects of global health including the social and economic aspects of communicable and non-communicable diseases, health systems research, policy and implementation, and the evaluation of disease control programmes and healthcare delivery solutions. It aims to stimulate scientific and policy debate and provide a forum for analysis and opinion sharing for individuals and organisations engaged in all areas of global health.