Back to the basics of time-of-flight secondary ion mass spectrometry data analysis of bio-related samples. II. Data processing and display.

IF 1.6 4区医学 Q4 BIOPHYSICS

Biointerphases Pub Date : 2023-05-01 DOI:10.1116/6.0002633

Daniel J Graham, Lara J Gamble

引用次数: 0

Abstract

This is the second half of a two-part Tutorial on the basics of the time-of-flight secondary ion mass spectrometry (ToF-SIMS) analysis of bio-related samples. Part I of this Tutorial series covers planning for a ToF-SIMS experiment, preparing and shipping samples, and collecting ToF-SIMS data. This Tutorial aims at helping the ToF-SIMS user to process, display, and interpret ToF-SIMS data. ToF-SIMS provides detailed chemical information about surfaces but comes with a steep learning. The purpose of this Tutorial is to provide the reader with a solid foundation in the ToF-SIMS data analysis.

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生物相关样品的飞行时间二次离子质谱数据分析的基本原理。II.数据处理和显示。

本教程由两部分组成，后半部分介绍飞行时间二次离子质谱 (ToF-SIMS) 分析生物相关样品的基础知识。本系列教程的第一部分包括 ToF-SIMS 实验的规划、样品的制备和运输以及 ToF-SIMS 数据的采集。本教程旨在帮助 ToF-SIMS 用户处理、显示和解释 ToF-SIMS 数据。ToF-SIMS 可提供详细的表面化学信息，但学习难度很大。本教程旨在为读者打下坚实的 ToF-SIMS 数据分析基础。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biointerphases 生物-材料科学：生物材料

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期刊介绍： Biointerphases emphasizes quantitative characterization of biomaterials and biological interfaces. As an interdisciplinary journal, a strong foundation of chemistry, physics, biology, engineering, theory, and/or modelling is incorporated into originated articles, reviews, and opinionated essays. In addition to regular submissions, the journal regularly features In Focus sections, targeted on specific topics and edited by experts in the field. Biointerphases is an international journal with excellence in scientific peer-review. Biointerphases is indexed in PubMed and the Science Citation Index (Clarivate Analytics). Accepted papers appear online immediately after proof processing and are uploaded to key citation sources daily. The journal is based on a mixed subscription and open-access model: Typically, authors can publish without any page charges but if the authors wish to publish open access, they can do so for a modest fee. Topics include: bio-surface modification nano-bio interface protein-surface interactions cell-surface interactions in vivo and in vitro systems biofilms / biofouling biosensors / biodiagnostics bio on a chip coatings interface spectroscopy biotribology / biorheology molecular recognition ambient diagnostic methods interface modelling adhesion phenomena.