Weight Regain After Bariatric Surgery: Scope of the Problem, Causes, Prevention, and Treatment.

IF 5.2 2区医学 Q1 ENDOCRINOLOGY & METABOLISM

Current Diabetes Reports Pub Date : 2023-03-01 DOI:10.1007/s11892-023-01498-z

Sabrena F Noria, Rita D Shelby, Katelyn D Atkins, Ninh T Nguyen, Kishore M Gadde

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引用次数: 9

Abstract

Purpose of review: Although bariatric surgery is the most effective treatment of severe obesity, a proportion of patients experience clinically significant weight regain (WR) with further out from surgery. The purpose of this review is to summarize the prevalence, predictors, and causes of weight regain.

Recent findings: Estimating the prevalence of WR is limited by a lack of consensus on its definition. While anatomic failures such as dilated gastric fundus after sleeve gastrectomy and gastro-gastric fistula after Roux-en-Y gastric bypass can lead to WR, the most common causes appear to be dysregulated/maladaptive eating behaviors, lifestyle factors, and physiological compensatory mechanisms. To date, dietary, supportive, behavioral, and exercise interventions have not demonstrated a clinically meaningful impact on WR, and there is limited evidence for pharmacotherapy. Future studies should be aimed at better defining WR to begin to understand the etiologies. Additionally, there is a need for non-surgical interventions with demonstrated efficacy in rigorous randomized controlled trials for the prevention and reversal of WR after bariatric surgery.

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减肥手术后体重恢复:问题的范围，原因，预防和治疗。

综述目的:尽管减肥手术是治疗重度肥胖最有效的方法，但仍有一部分患者在手术后出现临床显著的体重反弹(WR)。本综述的目的是总结体重恢复的患病率、预测因素和原因。最近的发现:由于对WR的定义缺乏共识，估计WR的流行程度受到限制。虽然解剖失败，如袖胃切除术后胃底扩张和Roux-en-Y胃旁路术后胃瘘可导致WR，但最常见的原因似乎是饮食行为失调/适应不良、生活方式因素和生理代偿机制。到目前为止，饮食、支持、行为和运动干预尚未证明对WR有临床意义的影响，药物治疗的证据有限。未来的研究应旨在更好地定义WR，以开始了解病因。此外，还需要在严格的随机对照试验中证明预防和逆转减肥手术后WR有效的非手术干预措施。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Diabetes Reports 医学 -

CiteScore

9.80

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The goal of this journal is to publish cutting-edge reviews on subjects pertinent to all aspects of diabetes epidemiology, pathophysiology, and management. We aim to provide incisive, insightful, and balanced contributions from leading experts in each relevant domain that will be of immediate interest to a wide readership of clinicians, basic scientists, and translational investigators. We accomplish this aim by appointing major authorities to serve as Section Editors in key subject areas across the discipline. Section Editors select topics to be reviewed by leading experts who emphasize recent developments and highlight important papers published over the past year on their topics, in a crisp and readable format. We also provide commentaries from well-known figures in the field, and an Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research.