A rare case of Menetrier's disease-induced gastric outlet obstruction.

Abstract

A 66-year-old female patient was brought to the emergency department (ED) of our hospital. She had a 3-day history of epigastric discomfort, nausea, coffee-ground emesis, and tarry stool passage. She also had gastric gastrointestinal stromal tumor (GIST) with partial gastrectomy in March 2021. The laboratory data demonstrated severe anemia, hypochlorhydria and hypoalbuminemia, with edema of her four limbs also noted. Emergent esophagogastroduodenoscopy (EGD) revealed hyperemic mucosal change in the body and a large ulcerated polypoid lesion in the posterior wall of the middle body spreading to pylorus-induced gastric outlet obstruction and much bloody material (Figure 1A), with biopsy reporting chronic gastritis and no evidence of Helicobacter pylori (H.P.) infection. The abdominal computed tomography scans (CT scans) showed gastric mucosal thickening along the greater curvature and antrum portion (Figure 1B). Although there was no evidence of malignancy, symptoms including epigastric