Diversity of transgenes in sustainable management of insect pests.

IF 2.7 3区生物学 Q2 BIOCHEMICAL RESEARCH METHODS

Transgenic Research Pub Date : 2023-10-01 Epub Date: 2023-08-12 DOI:10.1007/s11248-023-00362-w

V Rakesh, Vinay K Kalia, Amalendu Ghosh

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引用次数: 1

Abstract

Insecticidal transgenes, when incorporated and expressed in plants, confer resistance against insects by producing several products having insecticidal properties. Protease inhibitors, lectins, amylase inhibitors, and chitinase genes are associated with the natural defenses developed by plants to counter insect attacks. Several toxin genes are also derived from spiders and scorpions for protection against insects. Bacillus thuringiensis Berliner is a microbial source of insecticidal toxins. Several methods have facilitated the large-scale production of transgenic plants. Bt-derived cry, cyt, vip, and sip genes, plant-derived genes such as lectins, protease inhibitors, and alpha-amylase inhibitors, insect cell wall-degrading enzymes like chitinase and some proteins like arcelins, plant defensins, and ribosome-inactivating proteins have been successfully utilized to impart resistance to insects. Besides, transgenic plants expressing double-stranded RNA have been developed with enhanced resistance. However, the long-term effects of transgenes on insect resistance, the environment, and human health must be thoroughly investigated before they are made available for commercial planting. In this chapter, the present status, prospects, and future scope of transgenes for insect pest management have been summarized and discussed.

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转基因在害虫可持续管理中的多样性。

杀虫转基因在植物中结合和表达时，通过产生几种具有杀虫特性的产品来增强对昆虫的抗性。蛋白酶抑制剂、凝集素、淀粉酶抑制剂和几丁质酶基因与植物为抵御昆虫攻击而开发的天然防御系统有关。一些毒素基因也来源于蜘蛛和蝎子，以保护它们免受昆虫的侵害。苏云金芽孢杆菌是一种杀虫毒素的微生物来源。几种方法促进了转基因植物的大规模生产。Bt衍生的cry、cyt、vip和sip基因，植物衍生的基因如凝集素、蛋白酶抑制剂和α-淀粉酶抑制剂，昆虫细胞壁降解酶如几丁质酶和一些蛋白质如arcelins、植物防御素和核糖体失活蛋白已被成功用于赋予昆虫抗性。此外，表达双链RNA的转基因植物已被开发出具有增强的抗性。然而，在将转基因用于商业种植之前，必须彻底研究转基因对昆虫抗性、环境和人类健康的长期影响。在本章中，对转基因在害虫管理中的现状、前景和未来范围进行了总结和讨论。

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来源期刊

Transgenic Research 生物-生化研究方法

CiteScore

5.40

自引率

0.00%

发文量

审稿时长

4-8 weeks

期刊介绍： Transgenic Research focusses on transgenic and genome edited higher organisms. Manuscripts emphasizing biotechnological applications are strongly encouraged. Intellectual property, ethical issues, societal impact and regulatory aspects also fall within the scope of the journal. Transgenic Research aims to bridge the gap between fundamental and applied science in molecular biology and biotechnology for the plant and animal academic and associated industry communities. Transgenic Research publishes -Original Papers -Reviews: Should critically summarize the current state-of-the-art of the subject in a dispassionate way. Authors are requested to contact a Board Member before submission. Reviews should not be descriptive; rather they should present the most up-to-date information on the subject in a dispassionate and critical way. Perspective Reviews which can address new or controversial aspects are encouraged. -Brief Communications: Should report significant developments in methodology and experimental transgenic higher organisms