Efficacy of Acellular Dermal Matrix Versus Connective Tissue Graft for Root Coverage in Patients with Gingival Recession: A Meta-Analysis.

IF 1.3 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE
Zhitao Wang, Tianyang Zhai
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引用次数: 0

Abstract

This study aimed to compare the efficacy of acellular dermal matrix (ADM) versus connective tissue graft (CTG) for root coverage in patients with gingival recession. Randomized controlled trials (RCTs) on the comparison of ADM with CTG in adult patients with gingival recession were searched in multiple databases updated on 15th May 2020. The quality of studies was evaluated using the upgraded Jadad scale. Included studies were assessed for percent root coverage (PRC), clinical attachment level (CAL), keratinized tissue (KT), probing depth (PD), recession width (RW) and recession depth (RD). Weighted mean difference (WMD) was used as the statistics for measurement data and the effect sizes were expressed as 95% confidence intervals (CI). Totally 24 RCTs were eligible for the final analysis. The patients accepting ADM had a higher gain in CAL (WMD: 0.250, 95%CI: 0.030-0.470, P=0.026) but a smaller gain in KT width (WMD: -0.440, 95%CI: -0.629--0.252, P<0.001) than those receiving CTG. No significant differences were found between the patients accepting ADM and those undergoing CTG in PRC (WMD: -1.608, 95%CI: -3.491-0.275, P=0.094), PD (WMD: 0.066, 95%CI: -0.005-0.137, P=0.067), RW (WMD: 0.065, 95%CI: -0.098-0.228, P=0.437) and RD (WMD: 0.109, 95%CI: -0.095-0.314, P=0.294). Overall, the ADM treatment for patients with gingival recession may be superior to CTG in gaining CAL, but CTG has a significant advantage over ADM in gaining KT width.

脱细胞真皮基质与结缔组织移植对牙龈萎缩患者牙根覆盖的疗效:一项荟萃分析。
本研究旨在比较脱细胞真皮基质(ADM)与结缔组织移植物(CTG)对牙龈萎缩患者牙根覆盖的疗效。在2020年5月15日更新的多个数据库中检索了ADM与CTG在成年牙龈退缩患者中比较的随机对照试验(RCTs)。采用升级版Jadad量表评价研究质量。纳入的研究评估了根覆盖百分比(PRC)、临床附着水平(CAL)、角化组织(KT)、探探深度(PD)、退退宽度(RW)和退退深度(RD)。计量资料采用加权平均差(WMD)进行统计,效应量用95%置信区间(CI)表示。共有24项rct符合最终分析的条件。接受ADM的患者CAL增加较高(WMD: 0.250, 95%CI: 0.030 ~ 0.470, P=0.026),但KT宽度增加较小(WMD: -0.440, 95%CI: -0.629 ~ 0.252, P=0.026)
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.90
自引率
6.20%
发文量
113
审稿时长
6-12 weeks
期刊介绍: The International Journal of Periodontics & Restorative Dentistry will publish manuscripts concerned with all aspects of clinical periodontology, restorative dentistry, and implantology. This includes pertinent research as well as clinical methodology (their interdependence and relationship should be addressed where applicable); proceedings of relevant symposia or conferences; and quality review papers. Original manuscripts are considered for publication on the condition that they have not been published or submitted for publication elsewhere.
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