Natural products as anthelmintics: safeguarding animal health

IF 12.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Angela A. Salim , Mark S. Butler , Mark A. T. Blaskovich , Ian R. Henderson , Robert J. Capon
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引用次数: 0

Abstract

Covering literature to December 2022

This review provides a comprehensive account of all natural products (500 compounds, including 17 semi-synthetic derivatives) described in the primary literature up to December 2022, reported to be capable of inhibiting the egg hatching, motility, larval development and/or the survival of helminths (i.e., nematodes, flukes and tapeworms). These parasitic worms infect and compromise the health and welfare, productivity and lives of commercial livestock (i.e., sheep, cattle, horses, pigs, poultry and fish), companion animals (i.e., dogs and cats) and other high value, endangered and/or exotic animals. Attention is given to chemical structures, as well as source organisms and anthelmintic properties, including the nature of bioassay target species, in vivo animal hosts, and measures of potency.

Abstract Image

天然驱虫产品:保障动物健康。
涵盖截至2022年12月的文献。本综述全面介绍了截至2022年12月的主要文献中描述的所有能够抑制虫卵孵化、运动、幼虫发育和/或蠕虫(即线虫、吸虫和绦虫)存活的天然产物(500种化合物,包括17种半合成衍生物)。这些寄生虫感染并危害商业牲畜(即羊、牛、马、猪、家禽和鱼)、伴侣动物(即狗和猫)和其他高价值、濒危和/或外来动物的健康和福利、生产力和生命。重点是化学结构,以及源生物和驱虫药的性质,包括生物测定目标物种的性质,体内动物宿主,和效力的措施。
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来源期刊
ACS Central Science
ACS Central Science Chemical Engineering-General Chemical Engineering
CiteScore
25.50
自引率
0.50%
发文量
194
审稿时长
10 weeks
期刊介绍: ACS Central Science publishes significant primary reports on research in chemistry and allied fields where chemical approaches are pivotal. As the first fully open-access journal by the American Chemical Society, it covers compelling and important contributions to the broad chemistry and scientific community. "Central science," a term popularized nearly 40 years ago, emphasizes chemistry's central role in connecting physical and life sciences, and fundamental sciences with applied disciplines like medicine and engineering. The journal focuses on exceptional quality articles, addressing advances in fundamental chemistry and interdisciplinary research.
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