Porcine epidemic diarrhea virus: an update overview of virus epidemiology, vaccines, and control strategies in South Korea.

IF 1.5 3区 农林科学 Q2 VETERINARY SCIENCES
Guehwan Jang, Duri Lee, Sangjune Shin, Jeonggyo Lim, Hokeun Won, Youngjoon Eo, Cheol-Ho Kim, Changhee Lee
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引用次数: 1

Abstract

Porcine epidemic diarrhea virus (PEDV) has posed significant financial threats to the domestic pig industry over the last three decades in South Korea. PEDV infection will mostly result in endemic persistence in the affected farrow-to-finish (FTF) herds, leading to endemic porcine epidemic diarrhea (PED) followed by year-round recurrent outbreaks. This review aims to encourage collaboration among swine producers, veterinarians, and researchers to offer answers that strengthen our understanding of PEDV in efforts to prevent and control endemic PED and to prepare for the next epidemics or pandemics. We found that collaboratively implementing a PED risk assessment and customized four-pillar-based control measures is vital to interrupt the chain of endemic PED in affected herds: the former can identify on-farm risk factors while the latter aims to compensate for or improve weaknesses via herd immunity stabilization and virus elimination. Under endemic PED, long-term virus survival in slurry and asymptomatically infected gilts ("Trojan Pigs") that can transmit the virus to farrowing houses are key challenges for PEDV eradication in FTF farms and highlight the necessity for active monitoring and surveillance of the virus in herds and their environments. This paper underlines the current knowledge of molecular epidemiology and commercially available vaccines, as well as the risk assessment and customized strategies to control PEDV. The intervention measures for stabilizing herd immunity and eliminating virus circulation may be the cornerstone of establishing regional or national PED eradication programs.

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猪流行性腹泻病毒:韩国病毒流行病学、疫苗和控制策略的最新概述。
在过去的30年里,猪流行性腹泻病毒(PEDV)对韩国国内养猪业构成了重大的经济威胁。PEDV感染将主要导致受影响的产犊至育肥猪群的地方性持续存在,导致地方性猪流行性腹泻(PED),随后全年反复暴发。这篇综述的目的是鼓励养猪生产者、兽医和研究人员之间的合作,提供答案,加强我们对PEDV的理解,努力预防和控制地方性PED,并为下一次或下一次大流行做好准备。我们发现,协同实施PED风险评估和定制的基于四支柱的控制措施对于中断受影响畜群中流行性PED的链至关重要:前者可以识别农场内的风险因素,而后者旨在通过稳定畜群免疫和消除病毒来弥补或改善弱点。在流行性PED的情况下,病毒在猪浆和无症状感染的后备母猪(“特洛伊猪”)中的长期存活是FTF农场根除PEDV的主要挑战,并强调了在畜群及其环境中积极监测和监测病毒的必要性。本文重点介绍了分子流行病学和市售疫苗的最新知识,以及PEDV的风险评估和定制控制策略。稳定群体免疫和消除病毒传播的干预措施可能是建立地区或国家PED根除计划的基石。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Veterinary Science
Journal of Veterinary Science 农林科学-兽医学
CiteScore
3.10
自引率
5.60%
发文量
86
审稿时长
1.3 months
期刊介绍: The Journal of Veterinary Science (J Vet Sci) is devoted to the advancement and dissemination of scientific knowledge concerning veterinary sciences and related academic disciplines. It is an international journal indexed in the Thomson Scientific Web of Science, SCI-EXPANDED, Sci Search, BIOSIS Previews, Biological Abstracts, Focus on: Veterinary Science & Medicine, Zoological Record, PubMed /MEDLINE, Index Medicus, Pubmed Central, CAB Abstracts / Index Veterinarius, EBSCO, AGRIS and AGRICOLA. This journal published in English by the Korean Society of Veterinary Science (KSVS) being distributed worldwide.
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