Migraine in bipolar disorder and schizophrenia: The hidden pain.

IF 1.1 4区医学 Q4 PSYCHIATRY

International Journal of Psychiatry in Medicine Pub Date : 2023-11-01 Epub Date: 2023-06-02 DOI:10.1177/00912174231178483

Nancy ElGizy, Aref Khoweiled, Mohamed A Khalil, Rehab Magdy, Dalia Khalifa

{"title":"Migraine in bipolar disorder and schizophrenia: The hidden pain.","authors":"Nancy ElGizy, Aref Khoweiled, Mohamed A Khalil, Rehab Magdy, Dalia Khalifa","doi":"10.1177/00912174231178483","DOIUrl":null,"url":null,"abstract":"Objective: This study examined the prevalence of comorbid migraine in patients with bipolar disorder and those with schizophrenia and also examined the association between migraine comorbidity and disease characteristics in both disorders.Methods: In this cross-sectional study, 150 patients with bipolar disorder and 150 with schizophrenia were evaluated for migraine diagnosis using the International Classification of Headache Disorders (3rd ed). Patients were selected from psychiatry outpatient clinics at Kasr Al Ainy hospitals, Cairo University. The Young Mania Rating Scale (YMRS) and the Hamilton Depression Rating Scale (HDRS) were administered to the bipolar group, whereas the Positive and Negative Syndrome Scale (PANSS) was administered to the schizophrenia group. Both groups were evaluated by the Clinical Global Impressions (CGI) scale.Results: The diagnosis of migraine was made in 34 (22.7%) of the bipolar group and 24 (16.0%) of the schizophrenia group. Patients with schizophrenia showed a significantly higher frequency and intensity of migraine attacks on the Migraine Disability Assessment scale than did the bipolar group (p < 0.001). In the bipolar group, there was no significant difference between patients with and without migraine on the YMRS, HDRS, and CGI. Among patients with schizophrenia, the duration of the migraine attacks was positively correlated with CGI scores (r = 0.40, p = 0.02).Conclusion: Migraine was found to be a significant comorbidity in patients with bipolar disorder and schizophrenia. However, the intensity and frequency of migraine attacks were higher in the schizophrenia than in the bipolar group.","PeriodicalId":50294,"journal":{"name":"International Journal of Psychiatry in Medicine","volume":null,"pages":null},"PeriodicalIF":1.1000,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Psychiatry in Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/00912174231178483","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/6/2 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"PSYCHIATRY","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: This study examined the prevalence of comorbid migraine in patients with bipolar disorder and those with schizophrenia and also examined the association between migraine comorbidity and disease characteristics in both disorders.

Methods: In this cross-sectional study, 150 patients with bipolar disorder and 150 with schizophrenia were evaluated for migraine diagnosis using the International Classification of Headache Disorders (3rd ed). Patients were selected from psychiatry outpatient clinics at Kasr Al Ainy hospitals, Cairo University. The Young Mania Rating Scale (YMRS) and the Hamilton Depression Rating Scale (HDRS) were administered to the bipolar group, whereas the Positive and Negative Syndrome Scale (PANSS) was administered to the schizophrenia group. Both groups were evaluated by the Clinical Global Impressions (CGI) scale.

Results: The diagnosis of migraine was made in 34 (22.7%) of the bipolar group and 24 (16.0%) of the schizophrenia group. Patients with schizophrenia showed a significantly higher frequency and intensity of migraine attacks on the Migraine Disability Assessment scale than did the bipolar group (p < 0.001). In the bipolar group, there was no significant difference between patients with and without migraine on the YMRS, HDRS, and CGI. Among patients with schizophrenia, the duration of the migraine attacks was positively correlated with CGI scores (r = 0.40, p = 0.02).

Conclusion: Migraine was found to be a significant comorbidity in patients with bipolar disorder and schizophrenia. However, the intensity and frequency of migraine attacks were higher in the schizophrenia than in the bipolar group.

查看原文本刊更多论文

双相情感障碍和精神分裂症患者的偏头痛：隐藏的疼痛。

目的：本研究调查了双相情感障碍患者和精神分裂症患者合并偏头痛的患病率，并研究了两种疾病中偏头痛合并症与疾病特征之间的关系。方法：在这项横断面研究中，150名双相情感障碍患者和150名精神分裂症患者使用国际头痛障碍分类法（第3版）对偏头痛的诊断进行了评估。患者选自开罗大学Kasr Al Ainy医院的精神科门诊。双相情感障碍组采用Young Mania量表（YMRS）和Hamilton抑郁量表（HDRS），而精神分裂症组采用阳性和阴性综合征量表（PANSS）。两组均采用临床整体印象（CGI）量表进行评估。结果：双相情感障碍组34例（22.7%）和精神分裂症组24例（16.0%）诊断为偏头痛。在偏头痛残疾评估量表上，精神分裂症患者的偏头痛发作频率和强度明显高于双相组（p＜0.001）。在双相组中，患有和不患有偏头痛的患者在YMRS、HDRS和CGI上没有显著差异。在精神分裂症患者中，偏头痛发作的持续时间与CGI评分呈正相关（r=0.40，p=0.02）。然而，精神分裂症患者偏头痛发作的强度和频率高于双相情感障碍组。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

International Journal of Psychiatry in Medicine 医学-精神病学

CiteScore

3.00

自引率

5.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The International Journal of Psychiatry in Medicine (IJPM) bridges the gap between clinical psychiatry research and primary care clinical research. Providing a forum for addressing: The relevance of psychobiological, psychological, social, familial, religious, and cultural factors in the development and treatment of illness; the relationship of biomarkers to psychiatric symptoms and syndromes in primary care...