Solitary pulmonary capillary hemangioma mimicking a preinvasive malignant lesion in an asymptomatic middle-aged female patient.

IF 0.5 Q4 ONCOLOGY
Yasuyuki Kanamoto, Hitoshi Dejima, Yuichi Saito, Toshihiro Haga, Tomohiro Watanabe, Yoshikane Yamauchi, Yuko Sasajima, Koji Saito, Masafumi Kawamura, Yukinori Sakao
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Abstract

Pulmonary capillary hemangiomatosis (PCH) is a rare disease characterized by a proliferation of capillaries in the alveolar septa, bronchial and venous walls, pleura, and regional lymph nodes. However, the etiology of the disease remains unknown due to its rarity. Therefore, we present a case of a solitary PCH lesion without symptoms in a 38-year-old female patient. According to computed tomography, she was diagnosed with lung carcinoma, indicated by a tiny nodule with ground-glass opacity detected in her right upper lung. However, no other lesions were detected on systemic examination. Consequently, partial lung resection was conducted, since the lesion was suspected of lung adenocarcinoma. Pathologic results showed that the thick alveolar septa were caused by capillary growth without cellular atypia and hardly any infiltration of inflammatory cells. Finally, we diagnosed the pulmonary lesion as PCH, although solitary PCH has previously been reported in a few case reports. Therefore, further case studies are essential to clarify the causes of PCH.

一例无症状中年女性患者的孤立性肺毛细血管瘤表现为侵袭前恶性病变。
肺毛细血管瘤病(PCH)是一种罕见的疾病,其特征是肺泡间隔、支气管和静脉壁、胸膜和区域淋巴结的毛细血管增生。然而,由于罕见,该病的病因尚不清楚。因此,我们报告一例38岁女性患者无症状的单发PCH病变。根据计算机断层扫描,她被诊断为肺癌,在她的右上肺检测到一个微小的结节和磨玻璃影。然而,全身检查未发现其他病变。因此,由于病变疑似肺腺癌,我们进行了部分肺切除术。病理结果显示,肺泡间隔增厚是由毛细血管增生引起的,无细胞异型性,几乎没有炎症细胞浸润。最后,我们将肺部病变诊断为PCH,尽管之前有少数病例报道过孤立性PCH。因此,进一步的个案研究是必要的,以澄清PCH的原因。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
自引率
14.30%
发文量
57
期刊介绍: This online-only journal publishes original case reports on all types of cancer. In particular, we welcome not only case reports of educational value in the diagnosis and treatment of cancers, but also reports on molecularly analyzed cancer cases, including gene mutations, gene fusions, gene expression, and changes in copy number, regardless of their known clinical significance. Assessing the molecular analysis of a tumor usually requires a “cancer conference” in which experts from various fields discuss it. Even if the authors and their respective “cancer conference” were unable to determine the clinical significance of molecular changes at the time of submission and publication, their data may provide evidence that will help the scientific community develop precision medicine solutions in the future. We welcome case reports with reviews of the literature on similar cases, as they are more useful and valuable to readers than are reports of rare cases. International Cancer Conference Journal is the official publication of the Japan Society of Clinical Oncology (JSCO). - Presents an online-only collection of original case reports on all types of cancer - In particular, welcomes molecularly analyzed cancer cases - The Official Publication of the Japan Society of Clinical Oncology (JSCO)
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