Carbimazole-induced atypia - A mimicker of malignancy in fine-needle aspiration cytology.

IF 0.8 4区医学 Q4 PATHOLOGY

Indian Journal of Pathology and Microbiology Pub Date : 2023-07-01 DOI:10.4103/ijpm.ijpm_513_21

M Aswin Manikandan, B Shobana, S Marry Lilly, J Thanka

引用次数: 0

Abstract

A 20-year-old female presented with complaints of thyroid swelling and showed signs and symptoms of thyrotoxicosis and fine-needle aspiration cytology (FNAC) was requested by the surgeon. On examination of FNAC smear, it showed thyroid follicular cells with atypical features like bizarre giant cells, pseudo nuclear inclusions, and mitotic figure. Correlation between clinical history and cytomorphologic features was done and it was reported as atypical changes in thyroid probably due to carbimazole-induced changes. It helped the patient, as radical surgery and its untoward complications were avoided.

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氨甲唑诱导的非典型性——细针抽吸细胞学中恶性肿瘤的模拟物。

一名20岁的女性，主诉甲状腺肿胀，并表现出甲状腺毒症的体征和症状，外科医生要求进行细针穿刺细胞学检查（FNAC）。在FNAC涂片检查中，显示甲状腺滤泡细胞具有不典型的特征，如奇异的巨细胞、假核包涵体和有丝分裂图。将临床病史与细胞形态学特征进行了相关性研究，报告为甲状腺的不典型变化，可能是由于卡吡唑诱导的变化。它帮助了病人，避免了根治性手术及其不良并发症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian Journal of Pathology and Microbiology PATHOLOGY-

CiteScore

1.20

自引率

0.00%

发文量

422

审稿时长

1 months

期刊介绍： The journal will cover studies related to pathology including morbid anatomy, surgical pathology, clinical pathology, diagnostic cytopathology including gynecologic cytology and aspiration cytology, hematology including immuno-hematology and medical microbiology. The journal gives preference to clinically oriented studies over experimental and animal studies. The Journal would publish peer-reviewed original research papers, case reports, systematic reviews, meta-analysis, letters to the editor and brief communications. Review articles on current topics usually are invited by the editor.